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Table of Contents
Vol. 27, No. 2, 2010
Issue release date: March 2010
Section title: Novel Insights from Clinical Practice
Fetal Diagn Ther 2010;27:101–105
(DOI:10.1159/000275809)

Tricuspid Valve Dysplasia with Severe Tricuspid Regurgitation: Fetal Pulmonary Artery Size Predicts Lung Viability in the Presence of Small Lung Volumes

Nathan A.T.a · Marino B.S.c, d · Dominguez T.d · Tabbutt S.c, d · Nicolson S.a · Donaghue D.D.c, e · Spray T.L.b · Rychik J.c, e
Divisions of aCardiac Anesthesia, bCardiothoracic Surgery, cCardiology and dCritical Care Medicine, and eFetal Heart Program, Cardiac Center, Children’s Hospital of Philadelphia, and University of Pennsylvania, Philadelphia, Pa., USA

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Article / Publication Details

First-Page Preview
Abstract of Novel Insights from Clinical Practice

Received: May 19, 2009
Accepted: October 07, 2009
Published online: January 12, 2010
Issue release date: March 2010

Number of Print Pages: 5
Number of Figures: 1
Number of Tables: 1

ISSN: 1015-3837 (Print)
eISSN: 1421-9964 (Online)

For additional information: http://www.karger.com/FDT

Abstract

Congenital tricuspid valve disease (Ebstein’s anomaly, tricuspid valve dysplasia) with severe tricuspid regurgitation and cardiomegaly is associated with poor prognosis. Fetal echocardiography can accurately measure right atrial enlargement, which is associated with a poor prognosis in the fetus with tricuspid valve disease. Fetal lung volumetric assessments have been used in an attempt to predict viability of fetuses using ultrasonogram and prenatal MRI. We describe a fetus with tricuspid dysplasia, severe tricuspid regurgitation, right atrial enlargement and markedly reduced lung volumes. The early gestational onset of cardiomegaly with bilateral lung compression raised the possibility of severe lung hypoplasia with decreased broncho-alveolar development. Use of fetal echocardiography with measurement of pulmonary artery size combined with prenatal MRI scanning of lung volumes resulted in an improved understanding of this anomaly and directed the management strategy towards a successful Fontan circulation.

© 2010 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Novel Insights from Clinical Practice

Received: May 19, 2009
Accepted: October 07, 2009
Published online: January 12, 2010
Issue release date: March 2010

Number of Print Pages: 5
Number of Figures: 1
Number of Tables: 1

ISSN: 1015-3837 (Print)
eISSN: 1421-9964 (Online)

For additional information: http://www.karger.com/FDT


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