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Epidemiology of Major Eye Diseases Leading to Blindness in Europe: A Literature ReviewProkofyeva E. · Zrenner E.
Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany Corresponding Author
Dr. med. Elena Prokofyeva, MD, MPH, PhD
Institute for Ophthalmic Research
Centre for Ophthalmology, University of Tübingen
Frondsberstrasse 23, DE–72076 Tübingen (Germany)
The objective of this work was to study the epidemiology of major eye diseases leading to blindness in Europe through a systematic literature review. The literature search was performed using the Medline database (PubMed), with MeSH and free text search terms. Inclusion criteria for the studies were: (a) performed on a healthy population of Caucasian origin aged between 50 and 75 years; (b) diagnosed by ophthalmological examination in accordance with the International Classification of Diseases 10; (c) contained a detailed description of the sampling and diagnostic procedures and data resources; (d) sample size >500, and (e) published between 1990 and 2008. The results of 57 studies on the prevalence and incidence of age-related macular degeneration, diabetic retinopathy and glaucoma are reported, providing an up-to-date and comprehensive overview of these diseases in Europe from an epidemiological perspective.
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