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Cover

Immune Response and the Eye

Editor(s): Niederkorn J.Y. (Dallas, Tex.) 
Kaplan H.J. (Louisville, Ky.) 
Table of Contents
Vol. 92, No. , 2007
Section title: Paper
Niederkorn JY, Kaplan HJ (eds): Immune Response and the Eye. Chem Immunol Allergy. Basel, Karger, 2007, vol 92, pp 244-253
(DOI:10.1159/000099275)

Acute Retinal Necrosis

Kezuka T.a · Atherton S.b
aDepartment of Ophthalmology, Tokyo Medical University Hospital, Tokyo, Japan; bDepartment of Cellular Biology and Anatomy, Medical College of Georgia, Augusta, Ga., USA

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Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: January 30, 2007
Cover Date: 2007

Number of Print Pages: 10
Number of Figures: 0
Number of Tables: 0

ISBN: 978-3-8055-8187-5 (Print)
eISBN: 978-3-318-01404-4 (Online)

Abstract

Acute retinal necrosis (ARN) is a rare disease that is usually caused by one of the three neurotropic human herpesviruses - herpes simplex virus type 1(HSV-1), HSV-2 and varicella-zoster virus (VZV). Although much is known about the clinical course of the disease and its treatment and about the viruses that cause it, comparatively little is known about its pathogenesis. This article will review the history of ARN, the typical clinical findings, and methods of diagnosis. Information from studies of the mouse model of ARN including development of anterior chamber-associated immune deviation (ACAID) and routes of spread will be reconsidered, and the combined information from human and mouse studies will be discussed to suggest mechanisms that contribute to the pathogenesis of ARN in human patients. Finally, puzzles and questions about the disease will be considered.


Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: January 30, 2007
Cover Date: 2007

Number of Print Pages: 10
Number of Figures: 0
Number of Tables: 0

ISBN: 978-3-8055-8187-5 (Print)
eISBN: 978-3-318-01404-4 (Online)


Copyright / Drug Dosage / Disclaimer

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.