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Vol. 44, No. 3, 2010
Issue release date: July 2010
Section title: Original Paper
Free Access
Caries Res 2010;44:317–322

Use of ICDAS Combined with Quantitative Light-Induced Fluorescence as a Caries Detection Method

Ferreira Zandoná A.a · Santiago E.b · Eckert G.c · Fontana M.d · Ando M.a · Zero D.T.a
aDepartment of Preventive and Community Dentistry, Indiana University School of Dentistry, and bDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Ind.; cDepartment of Cariology and Restorative Sciences, University of Michigan School of Dentistry, Ann Arbor, Mich.; dResearch Center, University of Puerto Rico School of Dentistry, San Juan, P.R., USA
email Corresponding Author

Andréa Ferreira Zandoná

415 Lansing Street, OH-144

Indianopolis, IN 46202 (USA)

Tel. +1 317 274 3409, Fax +1 317 274 5425



  1. Amaechi BT, Higham SM: Quantitative light-induced fluorescence: a potential tool for general dental assessment. J Biomed Opt 2002;7:7–13.
  2. Amaechi BT, Podoleanu A, Higham SM, Jackson DA: Correlation of quantitative light- induced fluorescence and optical coherence tomography applied for detection and quantification of early dental caries. J Biomed Opt 2003;8:642–647.
  3. Ando M, Eckert GJ, Stookey GK, Zero DT: Effect of imaging geometry on evaluating natural white-spot lesions using quantitative light-induced fluorescence. Caries Res 2004a;38:39–44.
  4. Ando M, Gonzalez-Cabezas C, Isaacs RL, Eckert GJ, Stookey GK: Evaluation of several techniques for the detection of secondary caries adjacent to amalgam restorations. Caries Res 2004b;38:350–356.
  5. Ando M, Hall AF, Eckert GJ, Schemehorn BR, Analoui M, Stookey GK: Relative ability of laser fluorescence techniques to quantitate early mineral loss in vitro. Caries Res 1997;31:125–131.
  6. Ando M, van der Veen MH, Schemehorn BR, Stookey GK: Comparative study to quantify demineralized enamel in deciduous and permanent teeth using laser- and light-induced fluorescence techniques. Caries Res 2001;35:464–470.
  7. Angmar-Mansson B, ten Bosch JJ: Quantitative light-induced fluorescence (QLF): a method for assessment of incipient caries lesions. Dentomaxillofac Radiol 2001;30:298–307.
  8. Buchalla W, Lennon AM, van der Veen MH, Stookey GK: Optimal camera and illumination angulations for detection of interproximal caries using quantitative light-induced fluorescence. Caries Res 2002;36:320–326.
  9. Burt BA, Kolker JL, Sandretto AM, Yuan Y, Sohn W, Ismail AI: Dietary patterns related to caries in a low-income adult population. Caries Res 2006;40:473–480.
  10. Cook SL, Martinez-Mier EA, Dean JA, Weddell JA, Sanders BJ, Eggertsson H, Ofner S, Yoder K: Dental caries experience and association to risk indicators of remote rural populations. Int J Paediatr Dent 2008;18:275–283.
  11. de Josselin de Jong E, Sundström F, Westerling H, Tranaeus S, ten Bosch JJ, Angmar-Mansson B: A new method for in vivo quantification of changes in initial enamel caries with laser fluorescence. Caries Res 1995;29:2–7.
  12. Ekstrand KR, Martignon S, Ricketts DJ, Qvist V: Detection and activity assessment of primary coronal caries lesions: a methodologic study. Oper Dent 2007;32:225–235.
  13. Ferreira Zandoná AG, Stookey GK, Eggertsson H, Wefel J, Katz B, Ofner S, Eckert G: Clinical validation study of QLF at Indiana; in Stookey GK (ed): Proceedings of the 6th Annual Indiana Conference. Indiana University School of Dentistry, 2003, vol 6, pp 237–252.
  14. Finlayson TL, Siefert K, Ismail AI, Sohn W: Psychosocial factors and early childhood caries among low-income African-American children in Detroit. Community Dent Oral Epidemiol 2007;35:439–448.
  15. Gonzalez-Cabezas C, Fontana M, Gomes-Moosbauer D, Stookey GK: Early detection of secondary caries using quantitative light-induced fluorescence. Oper Dent 2003;28:415–422.
  16. Heinrich-Weltzien R, Kühnisch J, Ifland S, Tranaeus S, Angmar-Mansson B, Stösser L: Detection of initial caries lesions on smooth surfaces by quantitative light-induced fluorescence and visual examination: an in vivo comparison. Eur J Oral Sci 2005;113:494–498.
  17. Ismail AI, Sohn W, Tellez M, Amaya A, Sen A, Hasson H, Pitts NB: The International Caries Detection and Assessment System (ICDAS): an integrated system for measuring dental caries. Community Dent Oral Epidemiol 2007;35:170–178.
  18. Ismail AI, Sohn W, Tellez M, Willem JM, Betz J, Lepkowski J: Risk indicators for dental caries using the International Caries Detection and Assessment System (ICDAS). Community Dent Oral Epidemiol 2008;36:55–68.
  19. Jablonski-Momeni A, Stachniss V, Ricketts DN, Heinzel-Gutenbrunner M, Pieper K: Reproducibility and accuracy of the ICDAS-II for detection of occlusal caries in vitro. Caries Res 2008;42:79–87.
  20. Kühnisch J, Berger S, Goddon I, Senkel H, Pitts N, Heinrich-Weltzien R: Occlusal caries detection in permanent molars according to WHO basic methods, ICDAS II and laser fluorescence measurements. Community Dent Oral Epidemiol 2008;36:475–484.
  21. Kühnisch J, Heinrich-Weltzien R, Senkel H, Sonju Clasen AB, Stösser L: Dental health and caries topography in 8-year-old German and immigrant children. Eur J Paediatr Dent 2001;2:191–196.
  22. Pitts N: ‘ICDAS’: an international system for caries detection and assessment being developed to facilitate caries epidemiology, research and appropriate clinical management. Community Dent Health 2004;21:193–198.
    External Resources
  23. Pretty IA: Caries detection and diagnosis: novel technologies. J Dent 2006;34:727–739.
  24. Pretty IA, Edgar WM, Higham SM: The effect of dehydration on quantitative light-induced fluorescence analysis of early enamel demineralization. J Oral Rehabil 2004;31:179–184.
  25. Pretty IA, Ellwood RP: Comparison of paired visual assessment and software analyses of changes in caries status over 6 months from fluorescence images. Caries Res 2007;41:115–120.
  26. Rodrigues JA, Hug I, Diniz MB, Lussi A: Performance of fluorescence methods, radiographic examination and ICDAS II on occlusal surfaces in vitro. Caries Res 2008;42:297–304.
  27. Rugarabamu PG, Poulsen S, Masalu JR: A longitudinal study of occlusal caries among schoolchildren in Dar es Salaam, Tanzania. Community Dent Oral Epidemiol 2002;30:47–51.
  28. Shi XQ, Tranaeus S, Angmar-Mansson B: Comparison of QLF and DIAGNOdent for quantification of smooth surface caries. Caries Res 2001;35:21–26.
  29. Sohn W, Ismail A, Amaya A, Lepkowski J: Determinants of dental care visits among low- income African-American children. J Am Dent Assoc 2007;138:309–318, quiz 395–396.
  30. Stookey GK: Quantitative light fluorescence: a technology for early monitoring of the caries process. Dent Clin North Am 2005;49:753–770.
  31. Tranaeus S, Al-Khateeb S, Björkman S, Twetman S, Angmar-Mansson B: Application of quantitative light-induced fluorescence to monitor incipient lesions in caries-active children: a comparative study of remineralisation by fluoride varnish and professional cleaning. Eur J Oral Sci 2001;109:71–75.
  32. Varma S, Banerjee A, Bartlett D: An in vivo investigation of associations between saliva properties, caries prevalence and potential lesion activity in an adult UK population. J Dent 2008;36:294–299.
  33. Zandoná AF, Zero DT: Diagnostic tools for early caries detection. J Am Dent Assoc 2006;137:1675–1684, quiz 1730, erratum 2007;138:298.
    External Resources