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| Ficolins in Innate Immunity Ficolins belong to the collectin family of proteins, constituting an ancient and important part of innate immunity. Ficolins can bind conserved pathogen-associated molecular pattern on the surface of microbes. The binding may result in activation of collectin-receptor bearing immune cells or, activation of complement via the lectin pathway. This theme issue will discuss recent understanding of the important roles played by ficolins in innate immune responses. |
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Copyright© 2012 S. Karger AG, Basel |
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