Congenital Cervical Rhabdomyosarcoma Arising in One Fetus of a Twin Pregnancy

Vol. 20, No. 4, 2005

Free Abstract Article (References) Article (PDF 419 KB)

Paper

Congenital Cervical Rhabdomyosarcoma Arising in One Fetus of a Twin Pregnancy
Kiyoshi Yoshino^a, Makoto Takeuchi^b, Masahiro Nakayama^b, Noriyuki Suehara^a

Departments of
^aObstetrics and
^bPathology, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan

Address of Corresponding Author

Fetal Diagn Ther 2005;20:291-295 (DOI: 10.1159/000085088)

Key Words

Congenital cervical rhabdomyosarcoma
Twin pregnancy
Chromosomal translocation
Ex utero intrapartum treatment

Abstract

Objective: To describe a huge congenital cervical rhabdomyosarcoma. Methods: We were recently confronted with a case of fetal solid neck mass arising in one fetus of a twin pregnancy. Prenatally, the cervical tumor was consistent with teratoma, but it was diagnosed histologically as a rhabdomyosarcoma. Genetic amniocentesis showed a mosaic pattern consisting of 46,XY/46,XY,t(2;8)(q35;q21.2). Results: EXIT procedure was proposed to the parents but declined. The twin with huge cervical tumor died in utero at 35 weeks' gestation due to hydrops fetalis. Conclusion: Fetal cervical rhabdomyosarcoma is an extremely rare condition that has not been previously reported, but should be considered in the presentation of fetal solid neck mass.

Author Contacts

Kiyoshi Yoshino, MD, PhD
Department of Obstetrics and Gynecology
Osaka University Faculty of Medicine
2-2 Yamadaoka, Suita, Osaka 565-0871 (Japan)
Tel. +81 6 6879 3355, Fax +81 6 6879 3359, E-Mail yoshino@gyne.med.osaka-u.ac.jp

Article Information

Received: March 31, 2004
Accepted after revision: May 11, 2004
Number of Print Pages : 5
Number of Figures : 5, Number of Tables : 0, Number of References : 11

Medline Abstract (ID 15980643)

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