Original Paper

Effect of Ultraviolet B Radiation on the Absorption Characteristics of Various Intraocular Lenses
Nilufer Kocak^a, Suleyman Kaynak^a, Turna Ilknur^b, Sebnem Ozkan^b, Gokhan Erdogan^c, Guray Cngl^a

Departments of
^aOphthalmology and
^bDermatology, Dokuz Eylul University,
^cInstitute of Technology, Center for Materials Research, Izmir, Turkey

Address of Corresponding Author

Ophthalmologica 2007;221:29-35 (DOI: 10.1159/000096519)

  Key Words

• Intraocular lens opacification
• Intraocular lens
• Ultraviolet B
• Ultraviolet filter

  Abstract

Background: The aim of this study was to determine the effect of ultraviolet B (UVB) exposure on UV filters of various intraocular lenses (IOLs). Methods: Eight samples each of the hydrophobic acrylic, hydrophilic acrylic and silicone IOLs were used. Four IOLs of each type was selected randomly as the control group while the remaining four IOLs of each type were exposed to a UVB dose of 1.4 J/cm² (2.40 mW/cm²) for 9.45 min, two times with a 4-week interval. IOLs were evaluated for any sign of opacification under microscope weekly. After a follow-up period of 16 weeks, spectrometry for UV filter absorption rates, scanning electron microscopy for deposit formation and energy dispersive X-ray analysis for elemental composition were performed for all IOLs, and findings of the control group IOLs were compared with those of the UVB-exposed IOLs. All these procedures were done at the Department of Ophthalmology, Faculty of Medicine, Dokuz Eylul University. Results: All the IOLs were free of any opacification during the follow-up period. Spectrometric analysis of their UV filters revealed a change in absorption rates in the hydrophilic acrylic and silicone IOLs compared to the control IOLs of the same type. Only the hydrophobic acrylic IOLs preserved the same UV absorption curve after UVB exposure. Conclusion: The pathogenesis of IOL opacification is still undetermined. Some reports claimed that the UV light was the responsible factor. Our experimental study revealed that high doses of UVB did not cause any opacification though they impaired the function of UV filters of the hydrophilic acrylic and silicone IOLs.

Copyright © 2007 S. Karger AG, Basel

  Author Contacts

Nilufer Kocak
1773 Sokak No:29 Tevfik Kocak Apt. D:3
TR-35510 Karsiyaka - Izmir (Turkey)
Tel. +90 532 785 4343, Fax +90 232 412 3099
E-Mail nkocak@yahoo.com

  Article Information

This study was presented in part as a free paper at the XXII Congress of the ESCRS, September 18-22, 2004, Paris, France.

Received: February 17, 2006
Accepted after revision: May 26, 2006
Number of Print Pages : 7
Number of Figures : 2, Number of Tables : 1, Number of References : 34