Clinical Study

Gamma Knife Radiosurgery in the Treatment of Choroidal Neovascularization (Wet-Type Macular Degeneration)
Mark A. Henderson^a, Shailaja Valluri^b, Simon S. Lo^a, Thomas C. Witt^c, Robert M. Worth^c, Ronald P. Danis^d, Robert D. Timmerman^e

Departments of
^aRadiation Oncology,
^bOphthalmology and
^cNeurosurgery, Indiana University Medical Center, Indianapolis, Ind.,
^dDepartment of Ophthalmology, University of Wisconsin Medical Center, Madison, Wisc., and
^eDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Tex., USA

Address of Corresponding Author

Stereotact Funct Neurosurg 2007;85:11-17 (DOI: 10.1159/000096634)

  Key Words

• Gamma knife
• Radiosurgery
• Choroidal neovascularization
• Macular degeneration

  Abstract

We evaluated retrospectively our institutional experience in the treatment of macular degeneration with gamma knife radiosurgery (GKR). Treatment was delivered in a single shot of 12 Gy. Seven patients were treated between March of 1999 and May of 2000. The median duration of follow-up was 2.2 years. The majority of patients maintained stable visual acuity after treatment. Our series indicates that GKR may be useful as a salvage treatment for patients who have failed or are ineligible for other treatments for their macular degeneration. Further studies are needed to better define the role of GKR in the treatment of macular degeneration.

Copyright © 2007 S. Karger AG, Basel

  Author Contacts

Simon S. Lo, MD
Department of Radiation Medicine
Arthur G. James Cancer Hospital, Ohio State University Medical Center
300 West 10th Avenue, Ste 083, Columbus, OH 43210 (USA)
Tel. +1 614 293 5610, Fax +1 614 293 4044, E-Mail simon.lo@osumc.edu

  Article Information

Published online: October 30, 2006
Number of Print Pages : 7
Number of Figures : 3, Number of Tables : 0, Number of References : 28