Original Paper

Effect of Fluoride Compounds on Enamel Erosion in vitro: A Comparison of Amine, Sodium and Stannous Fluoride
C. Ganss^a, N. Schlueter^a, M. Hardt^b, P. Schattenberg^a, J. Klimek<sup>a

a</sup>Department of Conservative and Preventive Dentistry, Dental Clinic, and
^bCentral Biotechnology Unit, Electron Microscopy Laboratory, Justus Liebig University Giessen, Giessen, Germany

Address of Corresponding Author

Caries Res 2008;42:2-7 (DOI: 10.1159/000111743)

  Key Words

• Enamel erosion
• Fluoride

  Abstract

The aim of the study was to evaluate the relevance of cations in different fluoride compounds for their effectiveness as anti-erosive agents. Human enamel samples underwent a de- and re-mineralisation procedure for 10 days. Erosive demineralisation was performed with 0.05 Mcitric acid (pH 2.3) 6 × 2 min daily followed by immersion in the test solution 6 × 2 min each. Test solutions were: SnCl₂ (815 ppm Sn; pH 2.6), NaF (250 ppm F; pH 3.5), SnF₂ (250 ppm F, 809 ppm Sn; pH 3.5), amine fluoride (AmF, 250 ppm F; pH 3.5), AmF/NaF (250 ppm F; pH 4.3), and AmF/SnF₂ (250 ppm F, 390 ppm Sn; pH 4.2). In the control group no fluoridation was performed. Mineral content was monitored by longitudinal microradiography. Finally, scanning electron microscopy was performed. The highest erosive mineral loss was found in the control group (48.0 ± 17.1 µm). Mineral loss was nearly completely inhibited by AmF/SnF₂ (5.7 ± 25.1 µm; p 0.001) and SnF₂ (-3.8 ± 14.4 µm; p 0.001) treatments. Groups treated with SnCl₂ (17.6 ± 19.5 µm; p 0.001) and NaF (13.2 ± 21.7 µm; p 0.001) showed a decrease in erosive mineral loss, AmF (41.6 ± 16.0 µm) and AmF/NaF (27.7 ± 28.4 µm) had no significant effect on erosion progression. The results indicate considerable differences between the fluoride compounds tested. Treatment with solutions containing SnF₂ was most effective.

Copyright © 2007 S. Karger AG, Basel

  Author Contacts

Dr. C. Ganss
Department of Conservative and Preventive Dentistry, Dental Clinic
Schlangenzahl 14, DE-35392 Giessen (Germany)
Tel. +49 641 99 46173, Fax +49 641 99 46169
E-Mail carolina.ganss@dentist.med.uni-giessen.de

  Article Information

Received: December 8, 2006
Accepted after revision: July 17, 2007
Published online: November 27, 2007
Number of Print Pages : 6
Number of Figures : 2, Number of Tables : 0, Number of References : 25