Kleine–Levin Syndrome: History and Brief Review

Vol. 60, No. 4, 2008

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Historical Note

Kleine-Levin Syndrome: History and Brief Review
J.M.S. Pearce

Emeritus Consultant Neurologist, Department of Neurology, Hull Royal Infirmary, Hull, UK

Address of Corresponding Author

Eur Neurol 2008;60:212-214 (DOI: 10.1159/000148694)

Key Words

Kleine-Levin syndrome
Episodic hypersomnia
Compulsive eating
Sexual behaviour
Diencephalon
Hypothalamus

Abstract

Episodic hypersomnia, compulsive excessive eating and erotic behaviour, with schizophrenic-like mental symptoms are the hallmarks of the rare Kleine-Levin syndrome. This paper traces the origins of its description back to the 18th century and the changing concepts of its complex organic-psychogenic aetiology. The eventual, spontaneous disappearance of the syndrome is unexplained.

Author Contacts

J.M.S. Pearce
304 Beverley Road
Anlaby, East Yorks HU10 7BG (UK)

Article Information

Received: October 26, 2007
Accepted: December 8, 2007
Published online: July 30, 2008
Number of Print Pages : 3
Number of Figures : 0, Number of Tables : 0, Number of References : 13

Medline Abstract (ID 18667831)

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