Hepatitis B Virus and Renal Transplantation

Vol. 90, No. 3, 2002

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Editorial Review

Hepatitis B Virus and Renal Transplantation
Fabrizio Fabrizi^a, Paul Martin^b, Claudio Ponticelli^a

^aDivision of Nephrology and Dialysis, Maggiore Hospital, IRCCS, Milan, Italy;
^bDivision of Digestive Diseases, Dumont-UCLA Transplant Center, UCLA School of Medicine, Los Angeles, Calif., USA

Address of Corresponding Author

Nephron 2002;90:241-251 (DOI: 10.1159/000049058)

Abstract

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Liver disease is a frequent complication [1-8] and an important cause of morbidity and mortality in renal transplant (RT) recipients. The most important agents of liver disease in RT recipients are hepatitis B virus (HBV) and hepatitis C virus (HCV); TTV and GBV-C/HGV infections are frequent in this population, but their role in the pathogenesis of liver damage is controversial. Numerous papers reported on the impact of HBV on the morbidity and mortality of RT recipients; the influence of HBV on patient and graft survival remains controversial. The aim of this report is to review the epidemiology and the clinical manifestations related to the presence of HBV in RT recipients. In addition, current recommendations about RT in HBV-infected patients will be mentioned.

Author Contacts

Dr. Fabrizio Fabrizi
Divisione di Nefrologia e Dialisi, Ospedale Maggiore
Via della Commenda 15
I-20122 Milano (Italy)
Tel. +39 02 55034552, Fax +39 02 55034550, E-Mail ponticel@polic.cilea.it

Article Information

Number of Print Pages : 11
Number of Figures : 1, Number of Tables : 3, Number of References : 91

Medline Abstract (ID 11867943)

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