Diagnostic Accuracy of Mini-Mental Status Examination and Revised Hasegawa Dementia Scale for Alzheimer’s Disease

Vol. 19, No. 5-6, 2005

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Original Research Article

Diagnostic Accuracy of Mini-Mental Status Examination and Revised Hasegawa Dementia Scale for Alzheimer's Disease
K.W. Kim^{a, c}, D.Y. Lee^{b, c}, J.H. Jhoo^e, J.C. Youn^f, Y.J. Suh^{d, g}, Y.H. Jun^b, E.H. Seo^d, J.I. Woo^{b, c,d}

^aDepartment of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do;
^bDepartment of Neuropsychiatry, Seoul National University Hospital;
^cSeoul National University College of Medicine, and
^dClinical Research Institute of Seoul National University Hospital, Seoul;
^eDepartment of Neuropsychiatry, Pundang Jesaeng Hospital, Daejin Medical Center, Seongnam-si, and
^fDepartment of Neuropsychiatry, Kyunggi Provincial Hospital for the Elderly, Yongin-si, Gyeonggi-do;
^gBK21 Research Division for Human Life Science, Seoul National University, Seoul, Korea

Address of Corresponding Author

Dement Geriatr Cogn Disord 2005;19:324-330 (DOI: 10.1159/000084558)

Key Words

Revised Hasegawa Dementia Scale
Mini-Mental Status Examination
Diagnostic accuracy
Alzheimer's disease
Education
Severity

Abstract

To compare the diagnostic accuracies of the Revised Hasegawa Dementia Scale (HDS-R) and Mini-Mental Status Examination (MMSE) for Alzheimer's diseases (AD), we administered them simultaneously to 82 AD patients and 82 age- and sex-matched nondemented control subjects. The area under the receiver operator curve (AUC) for AD of the HDS-R (AUC_HDS-R) and MMSE (AUC_MMSE) were bigger than 0.90 indicating that both tests are useful for detecting AD. However, AUC_HDS-R (0.952) was significantly larger than that of the AUC_MMSE(0.902) regardless of the educational level of the subjects, indicating that the HDS-R is more accurate than MMSE in diagnosing AD. Moreover, the superiority of the HDS-R (AUC_HDS-R = 0.894) to the MMSE (AUC_MMSE = 0.704) remained significant in mild AD patients alone, who are the focus of screening. In conclusion, the HDS-R is better than the MMSE as a screening instrument for AD.

Author Contacts

Jong-Inn Woo, MD, PhD, Department of Neuropsychiatry
Seoul National University, College of Medicine and Seoul National University Hospital
28 Yongon-dong, Chongno-gu, Seoul 110-744 (Korea)
Tel. +82 2 760 2456, Fax +82 2 762 3176
E-Mail jiwoomd@plaza.snu.ac.kr

Article Information

Accepted: November 1, 2004
Published online: March 22, 2005
Number of Print Pages : 7
Number of Figures : 0, Number of Tables : 5, Number of References : 17

Medline Abstract (ID 15785033)

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