Address of Corresponding Author

Ophthalmic Res 2005;37:150-155 (DOI: 10.1159/000085850)

  Key Words

• Reciprocity law
• Ultraviolet radiation
• Cataract
• -Tocopherol
• Rats

  Abstract

Purpose: The authors have previously described that the photochemical reciprocity law does not apply for ultraviolet radiation (UVR)-induced cataract. The aim of this study was to elucidate if failure of the reciprocity reverses with vitamin E (-tocopherol) administration. Methods: Altogether, 80 rats were divided into one group fed -tocopherol and one control group. For each group, half of rats were exposed to UVR for 5 min and the remaining rats for 15 min. Results: Lenses exposed to UVR for 5 min showed no difference in light scattering between -tocopherol-treated and untreated groups. Lenses exposed to UVR for 15 min showed significant difference in light scattering between -tocopherol-treated and untreated groups. Conclusions: Failure in exposure time-intensity reciprocity for UVR-induced cataract with exposures shorter than 30 min may be due to consumption of antioxidants in the lens.

Copyright © 2005 S. Karger AG, Basel

  Author Contacts

Marcelo Ayala
Örebro University Hospital
Eye Department
SE-70185 Örebro (Sweden)
Tel. +46 19 6020000, Fax +46 19 6022561, E-Mail marcelo.ayala@ste.ki.se

  Article Information

Received: June 9, 2004
Accepted: November 22, 2004
Published online: May 19, 2005
Number of Print Pages : 6
Number of Figures : 5, Number of Tables : 0, Number of References : 18