Evaluation of Intra-Renal Oxygenation by BOLD MRI

Vol. 103, No. 2, 2006

Free Abstract Article (Fulltext) Article (PDF 273 KB)

Radiologic Imaging

Evaluation of Intra-Renal Oxygenation by BOLD MRI
Pottumarthi V. Prasad

Department of Radiology, Evanston Northwestern Healthcare, Evanston, Ill., USA

Address of Corresponding Author

Nephron Clin Pract 2006;103:c58-c65 (DOI: 10.1159/000090610)

Key Words

Blood oxygenation level-dependent MRI
Magnetic resonance imaging
Acute renal failure
Hypertension
Renal transplantation
Diabetes
Blood flow
Nitric oxide

Abstract

This is a review of blood oxygenation level-dependent (BOLD) MRI as applied to the kidney. It has been shown that BOLD MRI measurements reflect changes in renal oxygenation, especially in the medulla. Renal medulla functions in a hypoxic milieu and is extremely sensitive to further decrease in blood flow or increase in oxygen consumption. Availability of a non-invasive technique such as BOLD MRI should allow for better understanding of the factors involved in the maintenance of renal oxygenation status, not only in animal models, but also in humans.

Author Contacts

Pottumarthi V. Prasad, PhD
Department of Radiology, Walgreen Jr. Bldg, Suite 507
Evanston Northwestern Healthcare
2650 Ridge Avenue, Evanston, IL 60201 (USA)
Tel. +1 847 570 1349, Fax +1 847 570 2942, E-Mail pprasad@enh.org

Article Information

Published online: March 10, 2006
Number of Print Pages : 8
Number of Figures : 2, Number of Tables : 0, Number of References : 60

Medline Abstract (ID 16543757)

Download Citation

Cited In

For non-native English speakers and international authors who would like assistance with their writing before submission, we suggest American Journal Experts for their scientific editing service.