Physical mapping of 3 candidate tumor suppressor genes relative to Beckwith-Wiedemann syndrome associated chromosomal breakpoints at 11p15.3

Vol. 68, No. 3-4, 1995

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Gene Mapping, Cloning, and Sequencing

Physical mapping of 3 candidate tumor suppressor genes relative to Beckwith-Wiedemann syndrome associated chromosomal breakpoints at 11p15.3
E. Redeker^a, M. Alders^a, J.M.N. Hoovers^a, C.W. Richard III^b, A. Westerveld^a, M. Mannens^a

^aInstitute of Human Genetics, University of Amsterdam, Academic Medical Centre, Amsterdam (The Netherlands) and
^bWestern Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh PA (USA)

Address of Corresponding Author

Cytogenet Cell Genet 1995;68:222-225 (DOI: 10.1159/000133917)

Abstract

A physical map encompassing the 3 Mb region containing the breakpoints of two Beckwith-Wiedemann Syndrome patients at chromosome band 11p15.3 is presented. The candidate tumor suppressor genes WEE1 ST5, and rhombotin, are positioned on this map relative to these Beckwith-Wiedemann syndrome translocation and inversion breakpoints.

Author Contacts

Request reprints from Dr. Bert Redeker, Institute of Human Genetics, University of Amsterdam, Academic Medical Centre, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands; telephone: 31-20-5665110; fax: 31-20-6918626.

Article Information

Received: 22 November 1993
Published online: May 15, 2008
Number of Print Pages : 4

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