Chronic Hemodynamic Effects of Propranolol Treatment in Dialysis-Refractory Hypertension

Vol. 22, No. 4-6, 1978

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Original Paper

Chronic Hemodynamic Effects of Propranolol Treatment in Dialysis-Refractory Hypertension
Q. Maggiore, C. Zoccali, G. Monzani, C. Contini

Centro di Fisiologia Clinica CNR and Divisione Nefrologica Ospedali Riuniti, Reggio di Calabria, and Laboratorio Fisiologia Clinica CNR, Pisa

Address of Corresponding Author

Nephron 1978;22:391-398 (DOI: 10.1159/000181481)

Key Words

Arterial hypertension
Dialysis and hypertension
Propranolol
Hemodynamics of uremic hypertension
Uremia

Abstract

The hemodynamic mechanism of the hypotensive effect of propranolol was studied by quantitative radiocardiography in 8 patients with dialysis-resistant hypertension. Propranolol treatment brought about a decrease in mean arterial pressure and peripheral vascular resistances. The cardiac index was slightly reduced only in the early stage of the treatment. No significant difference was found between patients on treatments lasting longer than 3 months and patients with dialysis-controlled hypertension. The results show that propranolol can be used safely as the sole antihypertensive agent in patients with dialysis-resistant hypertension.

Author Contacts

Prof. Quirino Maggiore, Ospedali Riuniti, Divisione Nefrologica, Via Sbarre Inferiori, 39, 89100, Reggio di Calabria (Italy)

Article Information

Received: February 10, 1977
Accepted: February 17, 1978
Published online: December 02, 2008
Number of Print Pages : 8

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