Danazol for the Treatment of Idiopathic Thrombocytopenic Purpura

Vol. 74, No. 2, 1985

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Original Paper

Danazol for the Treatment of Idiopathic Thrombocytopenic Purpura
M. Buelli, S. Cortelazzo, P. Viero, B. Minetti, B. Comotti, R. Bassan, T. Barbui

Divisione di Ematologia, Ospedali Riuniti di Bergamo, Italy

Address of Corresponding Author

Acta Haematol 1985;74:97-98 (DOI: 10.1159/000206176)

Key Words

Danazol
Idiopathic thrombocytopenic purpura
Platelet number

Abstract

Fourteen patients with idiopathic thrombocytopenic purpura (ITP) refractory to steroids and/or splenectomy were treated with danazol (200 mg 3 times a day) for 2 months. The following responses were achieved: excellent (platelet count > 100 × 10⁹/1) in 5 patients; good ( > 50 × 10⁹/1, but < 100 × 10⁹/1) in 2 patients, and poor in (no increase of platelet count) 7 patients. In three cases remission lasted more than 7 months. Danazol was well tolerated and in most patients better suited than steroids for long-term intake

Author Contacts

Prof. Tiziano Barbui, Divisione di Ematologia, Ospedali Riuniti di Bergamo, Largo Barozzi 1 I-24100 Bergamo (Italy)

Article Information

Received: May 13, 1985
Accepted: August 5, 1985
Published online: February 25, 2009
Number of Print Pages : 2

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