Fractional Excretion of Urea as a Guide to Renal Dysfunction

Vol. 12, No. 1-2, 1992

Free Abstract Article (PDF 2848 KB)

Clinical Study

Fractional Excretion of Urea as a Guide to Renal Dysfunction
Andre A. Kaplan, Orly F. Kohn

Division of Nephrology, Department of Medicine, University of Connecticut School of Medicine, Farmington, Conn., USA

Address of Corresponding Author

Am J Nephrol 1992;12:49-54 (DOI: 10.1159/000168417)

Key Words

Urea
Prerenal azotemia
Acute renal failure
Fractional excretion of urea
Fractional excretion of sodium
Renal perfusion
Congestive heart failure
Angiotensin converting enzyme inhibition

Abstract

The use of fractional excretion of sodium as a guide to renal perfusion is hampered by the prior use of natriuretic agents. The fractional excretion of urea (FEUr) has been shown to be affected by volume status. We, therefore, determined the value of the FEUr as a guide to renal perfusion. In 6 patients evaluated prospectively and in 87 patients evaluated retrospectively, a low FEUr ( 35 %) was found to be a sensitive index to renal perfusion, despite the prior administration of furosemide.

Author Contacts

Andre A. Kaplan, MD, Division of Nephrology, MC-1405, University of Connecticut Health Center, Farmington, CT 06030 (USA)

Article Information

Received: October 9. 1991
Accepted: March 1, 1992
Published online: October 28, 2008
Number of Print Pages : 6

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