Prevalence of Mitral Valve Prolapse in Chronic Lymphocytic Thyroiditis and Nongoitrous Hypothyroidism

Vol. 75, No. 4, 1988

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Original Paper

Prevalence of Mitral Valve Prolapse in Chronic Lymphocytic Thyroiditis and Nongoitrous Hypothyroidism
A. Brauman, T. Rosenberg, Y. Gilboa, M. Algom, L. Fuchs, Z. Schlesinger

Departments of Internal Medicine 'B', Endocrinology and Cardiology, Assaf Harofeh Medical Center, Zerifin and Sackler School of Medicine, Tel Aviv University, Israel

Address of Corresponding Author

Cardiology 1988;75:269-273 (DOI: 10.1159/000174383)

Key Words

Autoimmunity
Chronic lymphocytic thyroiditis
Mitral valve prolapse
Nongoitrous hypothyroidism

Abstract

An increased prevalence of mitral valve prolapse has been found in Graves' disease and a common autoimmune etiology has been suggested for both disorders. We investigated the prevalence of mitral valve prolapse in 87 patients with autoimmune chronic lymphocytic thyroiditis, 50 patients with nongoitrous hypothyroidism and 111 healthy control subjects. Mitral valve prolapse was found in 16.09% of patients with chronic lymphocytic thyroiditis compared to 6 and 5.4% in nongoitrous hypothyroidism and normal controls, respectively. The result is statistically significant, p < 0.02, and confirms that the prevalence of mitral valve prolapse is significantly increased in patients with autoimmune disorders of the thyroid gland, when compared to normals and nonautoimmune conditions.

Author Contacts

Prof. Y. Gilboa, Department of Medicine 'B' and Endocrinology, Assaf Harofeh Medical Center, Zerifin 70300 (Israel)

Article Information

Received: June 5, 1987
Accepted after revision: November 8, 1987
Published online: November 11, 2008
Number of Print Pages : 5

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