A Clinical and Immunopathologic Dissection of Rapidly Progressive Glomerulonephritis

Vol. 22, No. 1-3, 1978

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Original Paper

A Clinical and Immunopathologic Dissection of Rapidly Progressive Glomerulonephritis
Richard J. Glassock

Department of Medicine, UCLA School of Medicine, Harbor General Hospital, Torrance, Calif.

Address of Corresponding Author

Nephron 1978;22:253-264 (DOI: 10.1159/000181457)

Key Words

Glomerulonephritis
Immune complex disease
Anti-basement membrane antibody disease

Abstract

This contribution seeks to illustrate the immunopathogenetic complexities of the syndrome of rapidly progressive glomerulonephritis. As with most of the clinical syndromes of glomerular disease, rapidly progressive glomerulonephritis may be dissected into a number of categories based upon combinations of clinical, morphologic and immunologic observations. It has been demonstrated that such observations have an important bearing on the natural history, prognosis and treatment of this syndrome. Much remains to be learned, particularly with respect to etiological factors, the genesis of extracapillary proliferation and the means of modifying or preventing these diseases.

Author Contacts

Richard J. Glassock, MD Professor of Medicine, UCLA/Harbor General Hospital, Chief, Division of Nephrology and Hypertension, 1000 Carson Street, Torrance, CA 90509 (USA)

Article Information

Published online: December 02, 2008
Number of Print Pages : 12

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