Normal Fluctuations of Leucocyte Counts and the Response to Infection in Benign Familial Leucopenia

Vol. 87, No. 3, 1992

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Original Paper

Normal Fluctuations of Leucocyte Counts and the Response to Infection in Benign Familial Leucopenia
Michael A Weingarten, Ernesto Kahan, Arieh Brauner

Departments of Family Medicine and Occupational Health, Tel-Aviv University, Tel-Aviv; Kupat Holim Department of Family Medicine, Beilinson Medical Centre and Community Clinic, Rosh Haayin, Israel

Address of Corresponding Author

Acta Haematol 1992;87:126-128 (DOI: 10.1159/000204738)

Key Words

Infection
Leucopenia
Yemenites

Abstract

In a long-term follow-up of 47 Yemenite patients with benign familial leucopenia, the mean white-cell count was 4,578 with a standard deviation of 940. During bacterial infections, the average leucocyte increment was the same in leucopenic as in non-leucopenic subjects, leading to total leucocyte counts in the normal range in previously leucopenic subjects. The marked degree of variability makes clinical interpretation difficult when leucocyte counts are found between levels standardised as normal in sick patients previously known to be leucopenic.

Author Contacts

Dr. M.A. Weingarten, Department of Family Medicine, Building 130, Sheba Medical Centre, Tel-Hashomer 52641 (Israel)

Article Information

Received: September 9, 1991
Accepted: December 11, 1991
Published online: February 19, 2009
Number of Print Pages : 3

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