The Role of Carotid Stenosis in Vascular Cognitive Impairment

Vol. 46, No. 2, 2001

Free Abstract Article (Fulltext)

Review

The Role of Carotid Stenosis in Vascular Cognitive Impairment
Rahul Rao

Guy's King's and St Thomas' Medical School and Institute of Psychiatry, London, UK

Address of Corresponding Author

Eur Neurol 2001;46:63-69 (DOI: 10.1159/000050765)

Key Words

Carotid stenosis
Neuropsychological tests
Endarterectomy

Abstract

The role of carotid stenosis in vascular cognitive impairment was reviewed using Medline, EMBASE, PsychLit and PsychInfo databases using the words 'carotid stenosis', 'neuropsychological tests' and 'endarterectomy'. Limited evidence exists for frontal lobe dysfunction associated with carotid stenosis, but there is a lack of systematic and prospective studies carried out in consecutive patients, including appropriate neuropsychological and MRI assessment. Possible pathophysiological processes suggested for cognitive impairment associated with carotid stenosis are suggested; these include chronic ischaemia and lacunar infarction; such mechanisms and resultant pathologies may co-exist in the presence of large-artery atheroma.

Author Contacts

Dr. Rahul Rao, Job Ward, Thomas Guy House
Guy's Hospital, St Thomas' Street
London SE1 9RT (UK)
Tel. +44 297 232 0148, Fax +44 207 394 1097
E-Mail r.rao@nhsdoctor.org.uk

Article Information

Received: Received: October 16, 2000
Accepted: March 30, 2001
Number of Print Pages : 7
Number of Figures : 0, Number of Tables : 2, Number of References : 47

Medline Abstract (ID 11528153)

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