Review

New Insights into the Combined Burden of Type 2 Diabetes and Hypertension
Ricardo Padilla^a,b, Raymond O. Estacio<sup>a-c

a</sup>Denver Health,
^bSchool of Medicine, University of Colorado,
^cColorado Prevention Center, Denver, Colo., USA

Address of Corresponding Author

Heart Drug 2003;3:25-33 (DOI: 10.1159/000070905)

  Key Words

• Type 2 diabetes
• Hypertension
• Review

  Abstract

Hypertension and type 2 diabetes are very common medical conditions that often occur in combination. A large amount of clinical trial data has proven the significance of improving blood pressure (BP) in type 2 diabetic patients in order to prevent cardiovascular morbidity and mortality, diabetic nephropathy and end-stage renal disease. The goal BP for all type 2 diabetics should be below 130/80 mm Hg, and below 125/75 mm Hg in subjects with significant proteinuria. Most investigators agree that angiotensin-converting enzyme inhibitors should be the first-line agents because of their cardioprotective effects. In the end, it may be that the specific drug choice has less overall importance than the actual attainment of adequate BP control. Treatment of hypertension in type 2 diabetics will often require multiple agents to achieve the goal BP.

Copyright © 2003 S. Karger AG, Basel

  Author Contacts

Ricardo Padilla, MD
c/o Denver Health - Westside Neighborhood Health Center
Mail Code 3000, 1100 Federal Boulevard
Denver, CO 80204 (USA)
Tel. +1 303 436 4282, Fax +1 303 436 4448, E-Mail Rick.Padilla@DHHA.org

  Article Information

Received: November 13, 2002
Accepted after revision: March 3, 2003
Number of Print Pages : 9
Number of Figures : 0, Number of Tables : 1, Number of References : 56