Blood Pressure as a Risk Factor for Stroke and the Impact of Antihypertensive Treatment

Vol. 20, Suppl. 2, 2005

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Atherothrombotic Disease and Cerebral Ischemia.
Editor(s): Díez-Tejedor, E. (Madrid)

Etiological Factors of the Atherothrombotic Disease

Blood Pressure as a Risk Factor for Stroke and the Impact of Antihypertensive Treatment
Antonio C. Gil-Núñez^a, José Vivancos-Mora^b

^aStroke Unit, Department of Neurology, Hospital General Universitario Gregorio Marañón, and
^bHospital Universitario de La Princesa, Madrid, Spain

Address of Corresponding Author

Cerebrovasc Dis 2005;20 (Suppl. 2):40-52 (DOI: 10.1159/000089356)

Key Words

Review
Stroke
Prevention
Risk factor
Hypertension
Normotension
Renin-angiotensin system

Abstract

We review hypertension and blood pressure levels as risk factors for stroke and the impact of antihypertensive treatment on the prevention of first stroke event and of recurrent stroke, not only with respect to the prevention of vascular events but also the prevention of cognitive deterioration, dementia, and physical disability. We review whether pharmacological blockage of the renin-angiotensin system has additional long-term effects over that of control of blood pressure levels alone, and the benefit of treatment with antihypertensive drugs in normotensive patients. Therapeutic objectives for blood pressure levels after stroke are defined together with recommendations of drugs and doses which have been demonstrated to have the greatest benefit in the prevention of stroke.

Author Contacts

Antonio C. Gil-Núñez, MD
Stroke Unit, Department of Neurology
Hospital General Universitario Gregorio Marañón
Dr. Esquerdo, 46, ES-28007 Madrid (Spain)
Tel. +34 9158 68012, Fax +34 9158 68339, E-Mail agiln@meditex.es

Article Information

Published online: December 2, 2005
Number of Print Pages : 13
Number of Figures : 3, Number of Tables : 1, Number of References : 118

Medline Abstract (ID 16327253)

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