Regulation of Maternal Metabolism by Pituitary and Placental Hormones: Roles in Fetal Development and Metabolic Programming

Vol. 65, Suppl. 3, 2006

Free Abstract Article (Fulltext) Article (PDF 239 KB)

Understanding the Biology and Therapeutic Consequences of Being Born SGA.
Editor(s): Czernichow, P. (Paris), Dunger, D. (Cambridge), Lévy-Marchal, C. (Paris)

The Biology of Fetal Growth

Regulation of Maternal Metabolism by Pituitary and Placental Hormones: Roles in Fetal Development and Metabolic Programming
M. Freemark

Division of Pediatric Endocrinology and Diabetes, Duke University Medical Center, Durham, N.C., USA

Address of Corresponding Author

Horm Res 2006;65 (Suppl. 3):41-49 (DOI: 10.1159/000091505)

Key Words

Growth hormone
Insulin
Insulin-like growth factor
Placental lactogen
Prolactin

Abstract

This review outlines the regulation of maternal metabolism by hormones, cytokines and growth factors, highlighting recent studies that implicate disordered somatolactogen signalling in the pathogenesis of perinatal growth failure and the development of the metabolic syndrome.

Author Contacts

M. Freemark
Department of Pediatrics, PO Box 3080
Room 306, Bell Research Building, Duke University Medical Center
Durham, NC 27710 (USA)
Tel. +1 919 684 8350, Fax +1 919 684 8613, E-Mail freem001@mc.duke.edu

Article Information

Published online: April 10, 2006
Number of Print Pages : 9
Number of Figures : 3, Number of Tables : 3, Number of References : 42

Medline Abstract (ID 16612113)

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