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Vol. 220, No. 3, 2006   

Free Abstract     Article (Fulltext)     Article (PDF 276 KB)     

Original Paper

Patent Blue: A Novel Vital Dye in Vitreoretinal Surgery
Stefan Mennel, Carsten H. Meyer, Andreas Tietjen, Eduardo B. Rodrigues, Jörg C. Schmidt

Department of Ophthalmology, Philipps University Marburg, Marburg, Germany

Address of Corresponding Author

Ophthalmologica 2006;220:190-193 (DOI: 10.1159/000091764)


 goto top of page Key Words

  • Chromovitrectomy
  • Patent blue
  • Vital dyes

 goto top of page Abstract

Purpose: To determine a novel vital dye (patent blue; Blueron®) for vitreoretinal surgery in a prospective consecutive case series. Methods: Five patients with either idiopathic epiretinal membrane (ERM; n = 2), proliferative vitreoretinopathy (n = 2), or a macular hole (n = 1) underwent a three-port pars plana vitrectomy. Patent blue assisted staining of the retinal surface followed by a consecutive peeling of the ERM (n = 4) or of the internal limiting membrane (ILM; n = 1) was performed. The main outcome measures were quality of intraoperative visualization of preretinal structures and postoperative visual acuity. Results: The dye induced a moderate staining (++) of the ERM and a mild staining (+) of the ILM. Complete ERM and ILM removal was successfully achieved in all cases. A mean visual improvement of three Snellen lines was observed 6 months postoperatively. No visual field defects or visible retinal pigment epithelial changes were present 6 months postoperatively. Conclusion: Patent blue, a novel dye for intraocular applications, may be added as an alternative dye in chromovitrectomy.

Copyright © 2006 S. Karger AG, Basel


 goto top of page Author Contacts

Stefan Mennel, MD
Department of Ophthalmology
Philipps University Marburg, Robert-Koch-Strasse 4
DE-35037 Marburg (Germany)
Tel. +49 6421 286 2660, Fax +49 6421 286 5678, E-Mail stefan.mennel@lycos.com


 goto top of page Article Information

This work was presented in part at the EURETINA, Barcelona 2005.

Received: May 19, 2005
Accepted after revision: November 11, 2005
Number of Print Pages : 4
Number of Figures : 1, Number of Tables : 1, Number of References : 16

 
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