Original Paper

Developmental Dyslexia: Re-Evaluation of the Corpus callosum in Male Adults
Fabrice Robichon^a, Pascal Bouchard^a, Jean-François Démonet^b, Michel Habib<sup>c

a</sup>Laboratoire d'Etude de l'Apprentissage et du Développement (CNRS ESA 5022), Université de Bourgogne, Dijon, France;
^bINSERM U-455, Hôpital Purpan, CHU de Toulouse, France;
^cLaboratoire de Neurologie Cognitive, Hôpital Nord, CHU de Marseille, France

Address of Corresponding Author

Eur Neurol 2000;43:233-237 (DOI: 10.1159/000008182)

  Key Words

• Developmental dyslexia
• Corpus callosum
• Magnetic resonance imaging
• Angle

  Abstract

Using a new method based upon the measurement of four angles, we analyzed the corpus callosum of 23 adult male dyslexics and 25 age-matched controls on MRI sagittal scans. Two out of the four angles measured showed significant differences between the groups that are consistent with previous findings concerning the size of the corpus callosum in dyslexics. In particular, posterior regions are concerned, displaying a lowered corpus callosum in dyslexics. These findings are discussed in relation to cortical parietal asymmetries and possible hormonal events, referring to the testosterone hypothesis, that could occur in utero or in the perinatal period in the dyslexic population.

Copyright © 2000 S. Karger AG, Basel

  Author Contacts

Dr. Fabrice Robichon
L.E.A.D.-C.N.R.S. ESA 5022, Université de Bourgogne
6 boulevard Gabriel
F-21000 Dijon (France)
Tel. +33 380 39 57 21, Fax +33 380 39 57 67, E-Mail Fabrice.Robichon@u-bourgogne.fr

  Article Information

Received: Received: September 27, 1999
Accepted: December 3, 1999
Number of Print Pages : 5
Number of Figures : 3, Number of Tables : 1, Number of References : 28