Higher Content of 18:1 Trans Fatty Acids in Subcutaneous Fat of Persons with Coronarographically Documented Atherosclerosis of the Coronary Arteries

Vol. 47, No. 6, 2003

Article (References) Article (PDF 68 KB)

Original Paper

Higher Content of 18:1 Trans Fatty Acids in Subcutaneous Fat of Persons with Coronarographically Documented Atherosclerosis of the Coronary Arteries
P. Dlouhý^a, E. Tvrzická^b, B. Staňková^b, M. Vecka^b, A. Žák^b, Z. Straka^c, J. Fanta^d, J. Pachl^e, D. Kubisová^a, J. Rambousková^a, D. Bílková^f, M. Anděl^a

^aDivision of Nutrition, 3rd Faculty of Medicine,
^bDepartment of Medicine IV, 1st Faculty of Medicine, Charles University,
^cDepartment of Heart Surgery, Královské Vinohrady University Hospital,
^dDepartment of Surgery, 3rd Faculty of Medicine,
^eDepartment of Anesthesiology and Resuscitation, 3rd Faculty of Medicine, and
^fDepartment of Statistics and Probability, 4th Faculty, Institute of Economics, Prague, Czech Republic

Address of Corresponding Author

Annals of Nutrition & Metabolism 2003;47:302-305 (DOI: 10.1159/000072403)

Key Words

Trans fatty acid isomers
Hardened fats
Atherosclerosis
Ischemic heart disease

Abstract

Aim: To identify the total content of trans fatty acid (TFA) isomers and C18:1 trans isomers in subcutaneous fat samples from persons with atherosclerosis of the coronary arteries, as an indicator of dietary exposure. Methods: Using capillary gas chromatography, the authors determined total content of TFA isomers and C18:1 trans isomers in the subcutaneous fat of 34 patients with ischemic heart disease who had undergone aortocoronary bypass surgery and in 46 patients with no sign of coronary disease. Results: On average, the total TFAs in cardiac patients were 2.88 ± 1.19% of all fatty acids, in noncardiac patients 2.56 ± 0.89%. However, the difference is not statistically significant. The average concentration of C18:1 trans in cardiac patients (2.31 ± 1.09%) was statistically significantly higher (p = 0.05) than in the noncardiac group (1.95 ± 0.77%). Conclusions: The results obtained indicate a lower TFA load in comparison with previous studies in other countries. A higher concentration of 18:1 TFAs in the subcutaneous fat of patients with coronary disease might be an impulse to correct the dietary habits of this very high-risk population.

Author Contacts

Pavel Dlouhý
3rd Faculty of Medicine, Charles University
Ruská 87, CZ–100 00 Prague 10 (Czech Republic)
Fax +420 267102618
E-Mail Pavel.Dlouhy@lf3.cuni.cz

Article Information

Received: January 3, 2003
Accepted: June 11, 2003
Number of Print Pages : 4
Number of Figures : 0, Number of Tables : 2, Number of References : 29

Cited in Web of Science®

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