Original Paper

Color Doppler Imaging of Choroidal Circulation in Patients with Asymmetric Age-Related Macular Degeneration
Önder Üretmen^a, Cezmi Akkn^a, Tansu Erakgün^a, Refik Killi^b

Departments of
^aOphthalmology and
^bRadiology, Ege University School of Medicine, Izmir, Turkey

Address of Corresponding Author

Ophthalmologica 2003;217:137-142 (DOI: 10.1159/000068559)

  Key Words

• Age-related macular degeneration
• Choroidal blood flow
• Color Doppler imaging
• Choroidal neovascularisation

  Abstract

We aimed at evaluating the possible role of choroidal perfusion abnormalities in the development of choroidal neovascularisation (CNV) in patients with age-related macular degeneration (AMD). Twenty-six patients who had non-exudative AMD in the first eye and CNV secondary to AMD in the fellow eye were enrolled. Blood flow velocities, vessel pulsatilities and resistivities were measured from ophthalmic artery, nasal and temporal posterior ciliary arteries using colour Doppler imaging. Systolic and diastolic velocities were lower in eyes with CNV for all vessels, except for the systolic velocity of the nasal posterior ciliary artery (p >0.05). Pulsatility and resistivity indices were higher in eyes with CNV for all vessels. This difference was statistically significant for the resistivity index of the nasal and temporal posterior ciliary arteries (p = 0.032 and p = 0.021, respectively) and the pulsatility index of the nasal posterior ciliary artery (p = 0.035). We have shown that in patients with AMD choroidal blood flow is more impaired in the eyes with CNV than in the fellow eyes.

Copyright © 2003 S. Karger AG, Basel

  Author Contacts

Önder Üretmen, MD
Ege University School of Medicine
Department of Ophthalmology
TR-35100 Bornova-Izmir (Turkey)
Tel./Fax +90 232 388 1469, E-Mail uretmen@med.ege.edu.tr

  Article Information

This study was presented at the XIIth Congress of the European Society of Ophthalmology, SOE 1999, Stockholm.

Received: December 3, 2001
Accepted after revision: February 15, 2002
Number of Figures : 2, Number of Tables : 2, Number of References : 54