Cystic Fibrosis in the 21st Century Diabetes in Cystic Fibrosis Bridges N, Spowart K Bush A, Alton EWFW, Davies JC, Griesenbach U, Jaffe A (eds): Cystic Fibrosis in the 21st Century. Prog Respir Res. Basel, Karger, 2006, vol 34, pp 278-283 (DOI: 10.1159/000088609)
Abstract: Pancreatic-insufficient individuals with cystic fibrosis (CF) develop abnormalities in insulin secretion which can be detected in childhood. The prevalence of impaired glucose tolerance and diabetes increases with age. Lung function and clinical status deteriorate in the years prior to a diagnosis of diabetes and survival is reduced in individuals with diabetes. Regular screening with oral glucose tolerance tests combined with clinical vigilance allows for early intervention with insulin to prevent clinical decline.Diabetes management must take into account the complex medical and psychological issues for individuals with CF, aiming to maintain nutritional and clinical status and prevent long-term complications of diabetes. |
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Title Index
