Address of Corresponding Author

Pancreatology 2005;5:108-109 (DOI: 10.1159/000084786)

  Key Words

• Acute pancreatitis
• Lactobacillus paracasei subspecies tolerans
• 16S rDNA sequencing
• Antibiotic prophylaxis, acute pancreatitis
• Antibiotic sensitivity, Lactobacillus spp.
• Pancreatic necrosis infection

  Abstract

An immunocompetent patient recovering from gallstone-induced pancreatitis had to be readmitted due to abdominal pain, fever, and rapid deterioration. Computed tomography guided needle aspiration established the diagnosis of pancreatic necrosis infection; microbiological investigations revealed monoinfection with Lactobacillus paracasei subspecies tolerans. To our knowledge, this is the first description of a pancreatic necrosis infection due to L. paracasei in an immunocompetent patient without any known risk factors for Lactobacillus infections.

Copyright © 2005 S. Karger AG, Basel and IAP

  References

1.

Saez Roca G, Fernandez E, Diez JM, Garcia P, Castillo C, Sanbonmatsu S: Splenic abscess and empyema due to Lactobacillus species in an immunocompetent host. Clin Infect Dis 1998;26:498-499.

2.

Patel R, Cockerill FR, Porayko MK, Osmon DR, Ilstrup DM, Keating MR: Lactobacillemia in liver transplant patients. Clin Infect Dis 1994;18:207-212.

3.

Husni RN, Gordon SM, Washington JA, Longworth DL: Lactobacillus bacteremia and endocarditis: Review of 45 cases. Clin Infect Dis 1997;25:1048-1055.

4.

Brook I, Frazier EH: Significant recovery of nonsporulating anaerobic rods from clinical specimens. Clin Infect Dis 1993;16:476-480.

5.

Bayer AS, Chow AW, Betts D, Guze LB: Lactobacillemia - report of nine cases: Important clinical and therapeutic considerations. Am J Med 1978;64:808-813.

6.

Axelrod J, Keusch GT, Bottone E, Cohen SM, Hirschman SZ: Endocarditis caused by Lactobacillus plantarum. Ann Intern Med 1973;78:33-37.

7.

Griffiths JK, Daly JS, Dodge RA: Two cases of endocarditis due to Lactobacillus species: Antimicrobial susceptibility, review, and discussion of therapy. Clin Infect Dis 1992;15:250-255.

8.

Querol JM, Manresa F, Izquierdo J, Cisnal M: Lactobacillus pneumonia in a patient with oesophageal carcinoma. Eur Respir J 1989;2:589-591.

9.

Razavi B, Schilling M: Chondritis attributable to Lactobacillus after ear piercing. Diagn Microbiol Infect Dis 2000;37:75-76.

10.

Pederzoli P, Bassi C, Vesentini S, Campedelli A: A randomized multicenter clinical trial of antibiotic prophylaxis of septic complications in acute necrotizing pancreatitis with imipenem. Surg Gynecol Obstet 1993;176:480-483.

11.

Delcenserie R, Yzet T, Ducroix JP: Prophylactic antibiotics in treatment of severe acute alcoholic pancreatitis. Pancreas 1996;13:198-201.

12.

Sainio V, Kemppainen E, Puolakkainen P, Taavitsainen M, Kivisaari L, Valtonen V, Haapiainen R, Schroder T, Kivilaakso E: Early antibiotic treatment in acute necrotising pancreatitis. Lancet 1995;346:663-667.

13.

Nordback I, Sand J, Saaristo R, Paajanen H: Early treatment with antibiotics reduces the need for surgery in acute necrotizing pancreatitis - a single-center randomized study. J Gastrointest Surg 2001;5:113-118; discussion 118-120.

14.

Luiten EJ, Bruining HA: Antimicrobial prophylaxis in acute pancreatitis: Selective decontamination versus antibiotics. Baillières Best Pract Res Clin Gastroenterol 1999;13:317-330.

15.

Isenmann R, Runzi M, Kron M, Kahl S, Kraus D, Jung N, Maier L, Malfertheiner P, Goebell H, Beger HG: Prophylactic antibiotic treatment in patients with predicted severe acute pancreatitis: A placebo-controlled, double-blind trial. Gastroenterology 2004;126:997-1004.

  Author Contacts

W.J. Z'Graggen, MD
Inselspital, Freiburgstrasse
CH-3010 Bern (Switzerland)
Tel. +41 31 632 30 98, Fax +41 31 632 30 11
E-Mail werner.zgraggen@insel.ch

  Article Information

Published online: March 30, 2005
Number of Print Pages : 2
Number of Figures : 0, Number of Tables : 0, Number of References : 15

  Publication Details

Pancreatology

Vol. 5, No. 1, Year 2005 (Cover Date: 2005)

Journal Editor: M.V. Singer, Mannheim; C.W. Imrie, Glasgow
ISSN: 1424-3903 (print), 1424-3911 (Online)

For additional information: http://www.karger.com/pan

  Drug Dosage / Copyright

Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.