Home

search

Subjectguide
Journals
Books / Serials / Multimedia
Services
Services

Login for Subscribers
Logout

Sitemap
Help
Contacts


Logo







Vol. 17, No. 1, 2008 

View or print article as PDF (1235 KB)   
 
Journal Home
Journal Content
Guidelines
Editorial Board
Aims and Scope
Subscriptions
Medline Abstract (ID 18059096)
Medline Related Articles
Download Citation
Cited In

Original Paper

Pulmonary Ventilatory Functions and Obesity in Kuwait
Wafaa R. Al-Badera, J. Ramadanb, A. Nasr-Eldina, b, M. Barac-Nietob

aMinistry of Public Health, Hawali Health Area, Rumaythia Polyclinic, and
bDepartment of Physiology, Faculty of Medicine, Kuwait University, Kuwait

Address of Corresponding Author

Med Princ Pract 2008;17:20-26 (DOI: 10.1159/000109585)


 goto top of outline Key Words

  • Pulmonary function
  • Body mass index
  • Waist-to-hip ratio
  • Obesity

 goto top of outline Abstract

Objective: To study the relationship between obesity and pulmonary ventilatory functions in Kuwaiti adults. Subjects and Methods: A total of 200 male and 180 female Kuwaiti adults aged 20-65 years were investigated in six medical centers from April 2004 to March 2006. Parameters measured included forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), FEV1 as a percentage of FVC (FEV%); body mass index (BMI in kg/m2) and waist-to-hip ratio (W/H). Results: For the whole group, males or females, BMI (kg·m2) and W/H were poor individual predictors of pulmonary ventilatory functions. However, central adiposity (W/H) was associated with restrictive respiratory impairment (10.6-13.9% decrease in FEV1 and 10-12.3% decrease in FVC), independent of sex, age or height. In obese females and males (BMI >30), increasing severity of obesity was significantly associated (p < 0.05, R2 >0.06) associated with increasing restrictive respiratory impairment (8.7-14.4% decrease in FEV1 and 8-11.7% decrease in FVC), with no evidence of obstructive disease (FEV1/FVC >0.8). Conclusion: In adult Kuwaiti males and females, increase in body fat at BMI >30 or W/H >1 was associated with a restrictive effect on pulmonary ventilation.

Copyright © 2007 S. Karger AG, Basel


 goto top of outline References


1.
World Health Organization: Controlling the global obesity epidemic. Geneva, WHO, 2003. http/http//www.who.int/nutrition/topics/obesity/en/index.html. Accessed January 31, 2006.

2.
American Thoracic Society Lung function testing: selection of reference values and interpretative strategies. Am Rev Respir Dis 1991;144:1202-1218.External Resources

3.
Quanjer PH, Tammeeling GJ, Cotes JA, Pedresen OF, Peslin R, Yernault JC: Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Testing. European Community for Steel and Coal. Official Statement of European Respiratory Society. Eur Respir J 1993;6:5-40.External Resources

4.
Hutchinson J: On the capacity of the lungs, and on the respiratory functions, with a view of establishing a precise and easy method for detecting disease by spirometer. Med Chir Trans 1846;29:137-252.

5.
Baltopoulos G, Fildisis G, Karatazas S, Georgiakodis F, Myrianthefs P: Reference values and prediction equations for FVC and FEV1 in Greek elderly. Lung 2000;178:201-212.External Resources

6.
Paoletti P, Pistelli G, Fazzi P, Viegi G, Di Pede F, Giuliano G, Prediletto R, Carrozzi L, Polato R, Saetta M: Reference values for vital capacity and flow-volume curves from a general population study. Bull Eur Physiopathol Respir 1986;22:451-459.External Resources

7.
Lazarus R, Gore C J, Booth M, Owen N: Effects of body composition and fat distribution on ventilatory function in adults. Am J Clin Nutr 1998;68:35-41.External Resources

8.
Santana H, Zoico E, Tosoni P, Bissoli L, Olivieri M, Bosello O, Zamboni M: Relation between body composition, fat distribution, and lung function in elderly men. Am Clin Nutr 2001;73:827-831.External Resources

9.
Dockery DW, Ware JH, Ferris BG, Glicksberg DS, Fay ME, Spiro A, Speizer FE: Distribution of forced expiratory volume in one second and forced vital capacity in healthy, white adult, never-smokers in six US cities. Am Rev Respir Dis 1985;131:511-520.External Resources

10.
Luce JM: Respiratory complications of obesity. Chest 1980;78:626-631.External Resources

11.
Ray CS, Sue DY, Bary G, Hansen JE, Wasserman K: Effects of obesity on respiratory function. Am Rev Respir Dis 1983;128:501-506.External Resources

12.
Harik-Khan RI, Wise RA, Fleg JL: The effect of gender on the relationship between body fat distribution and lung function. J Clin Epidemiol 2001;54:399-406.External Resources

13.
Williamson DF: Measurement of waist-hip ratio, classification of obesity. Am J Hum Biol 1993;15:59-67.

14.
Cotes JE, Chinn DJ, Reed JW: Body mass, fat percentage, and fat-free mass as reference variables for lung function: effect on terms for age and sex. Thorax 2001;56:839-844.External Resources

15.
Schoenberg J, Beck G, Bouhuys A: Grow and decay of pulmonary function in healthy black and white. Respir Physiol 1978;33:367-393.External Resources

16.
Collins L, Hoberty P, Walker J, Flecher E, Peiris A: The effect of body fat distribution on pulmonary function tests. Chest 1995;107:1298-1302.External Resources

17.
Lazarus R, Sparrow D, Weiss ST: Effects of obesity and fat distribution on ventilatory function. Chest 1997;111:891-898.External Resources

18.
Al-Issa AN: Prevalence of obesity among adult Kuwaitis: across-sectional study. Int J Obes Relat Metab Disord 1995;19:431-433.External Resources


 goto top of outline Author Contacts

Dr. Jasem Ramadan
Department of Physiology, Faculty of Medicine
PO Box 24923, Safat 13110 (Kuwait)
Tel. +965 531 9594, Fax +965 533 8937
E-Mail Ramadan@hsc.edu.kw


 goto top of outline Article Information

Received: December 5, 2006
Revised: March 11, 2007
Published online: April 22, 2008
Number of Print Pages : 7
Number of Figures : 2, Number of Tables : 3, Number of References : 18


 goto top of outline Publication Details

Medical Principles and Practice (International Journal of the Kuwait University Health Sciences Centre)

Vol. 17, No. 1, Year 2008 (Cover Date: December 2007)

Journal Editor: Owunwanne, A. (Kuwait)
ISSN: 1011-7571 (Print), eISSN: 1423-0151 (Online)

For additional information: http://www.karger.com/MPP


 goto top of outline Drug Dosage / Copyright

Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.

   


copyright  © 2009 S. Karger AG, Basel
  Last update: 22/4/2008