The Insulinotropic Gut Hormone Glucagon-Like Peptide-1
An excellent summary of current knowledge
Glucagon-like peptide-1 (GLP-1) is a promising new therapeutic tool for the treatment of diabetes. Since the first reports describing its potent insulinotropic activity were published about a decade ago, knowledge of the incretin hormones, and GLP-1 in particular, has increased significantly. This timely volume summarizes what is now known about the molecular biology, physiology and pharmacology of GLP-1. Thorough coverage is given to the physiology of the hormone, including its generation, release and actions at pancreatic and extrapancreatic tissues. The intracellular mechanisms of GLP-1 are also described in detail. Discussion of the molecular biology includes the structure and functions of the genes coding for proglucagon and the GLP-1 receptor. A special feature of the book is the clinical information provided which includes data on the expression and release of GLP-1 and its potential use as a therapeutic agent for diabetes. Presenting the results of exciting new research, this book will be a valuable reference for endocrinologists, gastroenterologists, pharmacologists, physiologists and biochemists interested in this important hormone.
Frontiers in Diabetes,
Vol. 13
ISSN: 0251-5342
e-ISSN: 1662-2995
The Insulinotropic Gut Hormone Glucagon-Like Peptide-1
Editor(s):
Fehmann, H.C. (Marburg);
Göke, B. (Marburg)
VIII + 240 p.,
63 fig.,
20 tab.,
hard cover,
1997
Status: available
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ISBN: 978-3-8055-6165-5
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