Case Report

Recovery of Minimal Change Nephrotic Syndrome and Acute Renal Failure in a Patient withRenal Cell Carcinoma
Teresa Auguet^a, Alfons Lorenzo^a, Enrique Colomer^a, Alberto Zamora^a, Carmen García^b, Alberto Martínez-Vea^b, Cristóbal Richart^a, Jesús Àngel Oliver^b

Departments of
^a Internal Medicine, and
^b Nephrology, Hospital Universitari Joan XXIII, Rovira i Virgili University, Tarragona, Spain

Address of Corresponding Author

Am J Nephrol 1998;18:433-435 (DOI: 10.1159/000013365)

  Key Words

• Nephrotic syndrome
• Minimal-change glomerulopathy
• Acute renal failure
• Renal cell carcinoma

  Abstract

We describe a 78-year-old patient with nephrotic syndrome due to minimal-change glomerulopathy, associated with a renal adenocarcinoma. Oliguric acute renal failure requiring hemodialysis was also observed. Surgical removal of the tumor and corticosteroid therapy resulted in resolution of the nephrotic state and improvement of the renal function. Nephrotic syndrome is an unusual complication of renal cell carcinomas, and the association of minimal-change glomerulopathy (MCG) and solid tumors is particularly uncommon. In spite of this, MCG should be considered in the nephropathies causing nephrotic syndrome and acute renal failure in patients with renal malignancies.

  Author Contacts

Teresa Auguet, MD
Department of Internal Medicine, Hospital Universitari Joan XXIII
C/ Dr. Mallafré Guasch, 4
E-43007 Tarragona (Spain)
Tel. 977 295833, Fax 977 224011

  Article Information

Received: Received: February 20, 1997
Accepted: August 5, 1997
Number of Print Pages : 3
Number of Figures : 0, Number of Tables : 1, Number of References : 12