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Disinfection by Sodium Hypochlorite: Dialysis Applications

Toxicity and Safety of Topical Sodium Hypochlorite

Bruch M

Ronco C, Mishkin GJ (eds): Disinfection by Sodium Hypochlorite: Dialysis Applications. Contrib Nephrol. Basel, Karger, 2007, vol 154, pp 24-38 (DOI: 10.1159/000096812)

Article (PDF 80 KB)      Free Preview
   Opens in a new window Medline Abstract (ID 17099299)

Abstract:
The safety and toxicity of sodium hypochlorite is reviewed with particular correlation to topical use. Since sodium hypochlorite is one of the most widely used chemicals in the environment, its safety has been established by long use and toxicity profile. This chapter reviews recent toxicology testing including routine systemic LD50, topical LD50, topical toxicology, irritation and sensitization. The resulting toxicity or safety profile clarifies the safe topical use of electrolytically produced sodium hypochlorite solution (ExSept, Amuchina 10%).


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