Isolated Bone Marrow Natural Killer Cell Lymphoma with Central Nervous System Involvement Mimicking a Cerebral Infarct

Vol. 31, No. 3, 2008

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Clinical Case · Kasuistik

Isolated Bone Marrow Natural Killer Cell Lymphoma with Central Nervous System Involvement Mimicking a Cerebral Infarct
Ibrahim Adaletli^a, Celalettin Camci^b, Alper Sevinc^b, Efsun Urger^a, Harun Ozer^a, Ibrahim Sari^c

^a Istanbul University, Cerrahpasa Medical Faculty, Department of Radiology, Istanbul,
^bGaziantep University, Gaziantep Oncology Hospital, Department of Medical Oncology,
^c Gaziantep University, School of Medicine, Department of Pathology, Gaziantep, Turkey

Address of Corresponding Author

Onkologie 2008;31:115-117 (DOI: 10.1159/000113536)

Key Words

NK-cell lymphoma
Bone marrow involvement, CNS involvement
Cerebral infarct

Summary

Background: We describe the case of an isolated bone marrow natural killer (NK) cell lymphoma with central nervous system (CNS) involvement mimicking a cerebral infarct. CNS involvement in isolated bone marrow lymphoma has not been reported previously. Case Report: A 49-year-old man with complaints of fever, confusion, and agitation was presented. A bone marrow biopsy was performed to investigate the etiology of bicytopenia which was consistent with NK-cell lymphoma. Brain MRI findings were suggestive of a subacute infarct. Conclusion: Even if pathological signal changes of the brain without contrast enhancement resembling infarct are detected in patients with lymphoma on the magnetic resonance imaging, CNS involvement of the lymphoma should be kept in mind in the differential diagnosis.

Author Contacts

Alper Sevinc, MD, Gaziantep University, School of Medicine, Department of Medical Oncology, Sahinbey Medical Center, Gaziantep, 27310, Turkey, Tel. +90 342360-1314, Fax -1617, E-mail sevinc@gantep.edu.tr

Article Information

Published online: February 8, 2008
Number of Print Pages : 3
Number of Figures : 3, Number of Tables : 0, Number of References : 9

Medline Abstract (ID 18322414)

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