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The in focus collections provide a quick and convenient overview of content on a specific current topic from the Karger publishing program. Regularly updated, in focus helps you save time and effort in staying up to date.

Enjoy free online access to a selection of original articles, reviews and book chapters on causes, prevention and treatment of diabetes and its complications until the end of October 2010!

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2010 Publications

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Reviews Published in Journals
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Oral Protein Therapy for the Future Transport of Glycolipid-Modified Proteins: Vision or Fiction?
Walid K.H. Fakhoury, Corinne LeReun, Donna Wright
Pharmacology 2010;86:92-116 (DOI: 10.1159/000316642)

Abstract
PDF (1779 KB)
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A Meta-Analysis of Placebo-Controlled Clinical Trials Assessing the Efficacy and Safety of Incretin-Based Medications in Patients with Type 2 Diabetes
Walid K.H. Fakhoury, Corinne LeReun, Donna Wright
Pharmacology 2010;86:44-57 (DOI: 10.1159/000314690)

Abstract
PDF (219 KB)
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Hot Topics in Nephrology: A Debate
Should Microalbuminuria Ever Be Considered as a Renal Endpoint in Any Clinical Trial?

Debate: PRO Position. Hiddo J. Lambers Heerspink, Dick de Zeeuw
Am J Nephrol 2010;31:458-461 (DOI: 10.1159/000292501)
PDF (264 KB)

Debate: CON Position. Richard J. Glassock
Am J Nephrol 2010;31:462-465 (DOI: 10.1159/000313553)
PDF (116 KB)

Rebuttal: PRO Position. Dick de Zeeuw, Hiddo J. Lambers Heerspink
Am J Nephrol 2010;31:466-467 (DOI: 10.1159/000313562)
PDF (60 KB)

Rebuttal: CON Position. Richard J. Glassock
Am J Nephrol 2010;31:468-468 (DOI: 10.1159/000313583)
PDF (53 KB)

Editorial Perspective. Matthew R. Weir, George L. Bakris
Am J Nephrol 2010;31:469-470 (DOI: 10.1159/000292500)
PDF (72 KB)
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Dual RAS Therapy Not on Target, but Fully Alive
H.J. Lambers Heerspink, D. de Zeeuw
Nephron Clin Pract 2010;116:c137-c142 (DOI: 10.1159/000315882)

Abstract
PDF (200 KB)
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Die chirurgische Behandlung des metabolischen Syndroms
Rudolf A. Weiner
Viszeralmedizin 2010;26:8-12 (DOI: 10.1159/000278693)

Abstract
PDF (150 KB)
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C-Peptide as a Therapeutic Tool in Diabetic Nephropathy
Claire E. Hills, Nigel J. Brunskill, Paul E. Squires
Am J Nephrol 2010;31:389-397 (DOI: 10.1159/000289864)

Abstract
PDF (636 KB)
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Personalized Prognosis and Diagnosis of Type 2 Diabetes Vision or Fiction?
Günter Müller
Pharmacology 2010;85:168-187 (DOI: 10.1159/000283780)

Abstract
PDF (1379 KB)
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Cystic Fibrosis-Related Diabetes in Childhood
Stephen M.P. O'Riordan, Mehul T. Dattani, Peter C. Hindmarsh
Horm Res Paediatr 2010;73:15-24 (DOI: 10.1159/000271912)

Abstract
PDF (322 KB)
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Diabetic Kidney Disease: Act Now or Pay Later
Robert C. Atkins, Paul Zimmet
Am J Nephrol 2010;31:I-IV (DOI: 10.1159/000280547)

Abstract
PDF (88 KB)

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Reviews Published in a Book
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Experimental Approaches to Diabetic Retinopathy

Frontiers in Diabetes, Vol. 20
Editors: Hammes, H.-P. (Mannheim); Porta, M. (Torino)
VIII + 232 p., 47 fig., 25 in color, 7 tab., hard cover, 2010

Full Details

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Chapters of Interest:

From Bedside to Bench and Back: Open Problems in Clinical and Basic Research
Porta M, Hammes H-P

Abstract
PDF (136 KB)
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Growth Factors in the Diabetic Eye
Simó R, Hernández C

Abstract
PDF (330 KB)
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Neuroglia in the Diabetic Retina
Bringmann A, Reichenbach A

Abstract
PDF (671 KB)

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Original Papers Published in Journals
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Feasibility and Efficiency of Indirect Lifestyle Interventions in Offspring of Type 2 Diabetic Patients
M. Nishigaki, A. Ota, T. Kusakabe, C. Matsuzaki, S. Taguchi, K. Kazuma
Public Health Genomics (DOI: 10.1159/000294217)

Abstract
PDF (292 KB)
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Incidence of Childhood Diabetes in Children Aged Less than 15 Years and Its Clinical and Metabolic Characteristics at the Time of Diagnosis: Data from the Childhood Diabetes Registry of Saxony, Germany
Angela Galler, Thoralf Stange, Gabriele Müller, Andrea Näke, Christian Vogel, Thomas Kapellen, Heike Bartelt, Hildebrand Kunath, Rainer Koch, Wieland Kiess, Ulrike Rothe, for the Childhood Diabetes Registry in Saxony, Germany
Horm Res Paediatr (DOI: 10.1159/000303141)

Abstract
PDF (157 KB)
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Comparison of Intravitreal Bevacizumab versus Triamcinolone for the Treatment of Diffuse Diabetic Macular Edema
Thomas C. Kreutzer, Rashid Al Saeidi, Daniel Kook, Armin Wolf, Michael W. Ulbig, Aljoscha S. Neubauer, Christos Haritoglou
Ophthalmologica 2010;224:258-264 (DOI: 10.1159/000284466)

Abstract
PDF (157 KB)
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Renoprotective Effects of Various Angiotensin II Receptor Blockers in Patients with Early-Stage Diabetic Nephropathy
Tsukasa Nakamura, Nobuharu Fujiwara, Eiichi Sato, Yoshihiko Ueda, Takeshi Sugaya, Hikaru Koide
Kidney Blood Press Res 2010;33:213-220 (DOI: 10.1159/000316707)

Abstract
PDF (214 KB)
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Circulating Levels of the Adipokine Chemerin in Gestational Diabetes Mellitus
Dörte Pfau, Holger Stepan, Jürgen Kratzsch, Michael Verlohren, Hans-Joachim Verlohren, Kathrin Drynda,
Ulrike Lössner, Matthias Blüher, Michael Stumvoll, Mathias Fasshauer
Horm Res Paediatr 2010;74:56-61 (DOI: 10.1159/000282114)

Abstract
PDF (353 KB)
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Screening Markers of Impaired Glucose Tolerance in the Obese Pediatric Population
J. Tsay, C. Pomeranz, A. Hassoun, S.O. Zandieh, J. Rutledge, M.G. Vogiatzi, S.E. Oberfield, R. Motaghed
Horm Res Paediatr 2010;73:102-107 (DOI: 10.1159/000277625)

Abstract
PDF (205 KB)
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Nutritional Counseling for Diabetic Patients: A Pilot Study in Hungarian Primary Care
Imre Rurik, Klára Ruzsinkó, Zoltán Jancsó, Magda Antal
Ann Nutr Metab 2010;57:18-22 (DOI: 10.1159/000314914)

Abstract
PDF (108 KB)
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Urinary Pigment Epithelium-Derived Factor as a Marker of Diabetic Nephropathy
Haibing Chen, Zhi Zheng, Rongxia Li, Junxi Lu, Yuqian Bao, Xiafang Ying, Rong Zeng, Weiping Jia
Am J Nephrol 2010;32:47-56 (DOI: 10.1159/000314326)

Abstract
PDF (725 KB)
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Relationship between Assays of Glycemia in Diabetic Subjects with Advanced Chronic Kidney Disease
Barry I. Freedman, Zak K. Shihabi, Lilian Andries, Cesar Y. Cardona, Todd P. Peacock, Joyce R. Byers, Gregory B. Russell, Robert J. Stratta, Anthony J. Bleyer
Am J Nephrol 2010;31:375-379 (DOI: 10.1159/000287561)

Abstract
PDF (221 KB)
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Metabolic Syndrome Is Associated with Learning and Recall Impairment in Middle Age
Jason J. Hassenstab, Victoria Sweat, Hannah Bruehl, Antonio Convit
Dement Geriatr Cogn Disord 2010;29:356-362 (DOI: 10.1159/000296071)

Abstract
PDF (174 KB)
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Relationship between Blood Glucose Control and Improved Cardiovascular Outcome after Stent Implantation in Diabetic Patients (Editorial Comment)
Itamar Raz
Cardiology 2010;116:48-50 (DOI: 10.1159/000314330)

Abstract
PDF (100 KB)
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Glycosylated Hemoglobin Is a Predictor of Major Adverse Cardiac Events after Drug-Eluting Stent Implantation in Patients with Diabetes Mellitus
Hiroyasu Ueda, Nobuhiro Mitsusada, Kuniyasu Harimoto, Masami Miyawaki, Yuji Yasuga, Hisatoyo Hiraoka
Cardiology 2010;116:51-57 (DOI: 10.1159/000314331)

Abstract
PDF (199 KB)
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Local Delivery of Angiotensin II Receptor Blockers into the Kidney Passively Attenuates Inflammatory Reactions during the Early Phases of Streptozotocin-Induced Diabetic Nephropathy through Inhibition of Calpain Activity
Fadia Kamal, Nadezhda Yanakieva-Georgieva, Honglan Piao, Tetsuo Morioka, Takashi Oite
Nephron Exp Nephrol 2010;115:e69-e79 (DOI: 10.1159/000)

Abstract
PDF (1140 KB)
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Features of Optical Coherence Tomography Are Predictive of Visual Outcomes after Intravitreal Bevacizumab Injection for Diabetic Macular Edema
Mi In Roh, Ji Hyun Kim, Oh Woong Kwon
Ophthalmologica 2010;224:374-380 (DOI: 10.1159/000313820)

Abstract
PDF (165 KB)
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Characteristics, Cardiovascular Comorbidity and Medicines Management in Patients with Type 2 Diabetes and CKD: Results of the IRIDIEM Study
P.E. Stevens, G. Schernthaner, S. Raptis, C. Wanner, A. Scherhag, N. Lameire
Kidney Blood Press Res 2010;33:119-128 (DOI: 10.1159/000313595)

Abstract
PDF (212 KB)
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Antibodies against Gluco-Oxidatively Modified Human Serum Albumin Detected in Diabetes-Associated Complications
Mohd. Wajid Ali Khan, Zulfkar Latief Qadrie, Wahid Ali Khan
Int Arch Allergy Immunol 2010;153:207-214 (DOI: 10.1159/000312639)

Abstract
PDF (191 KB)
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Diabetes in Primary Care: Prospective Associations between Depression, Nonadherence and Glycemic Control
Jörg Dirmaier, Birgit Watzke, Uwe Koch, Holger Schulz, Hendrik Lehnert, Lars Pieper, Hans-Ulrich Wittchen
Psychother Psychosom 2010;79:172-178 (DOI: 10.1159/000296135)

Abstract
PDF (168 KB)
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People with Impaired Glucose Tolerance and Impaired Fasting Glucose Are Similarly Susceptible to Cardiovascular Disease: A Study in First-Degree Relatives of Type 2 Diabetic Patients
Massoud Amini, Negar Horri, Maryam Zare, Sassan Haghighi, Seyed Mohsen Hosseini, Ashraf Aminorroaya, Silva Hovsepian
Ann Nutr Metab 2010;56:267-272 (DOI: 10.1159/000294752)

Abstract
PDF (147 KB)
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Regulation of the Glutamate Transporter EAAT4 by PIKfyve
Ioana S. Alesutan, Oana N. Ureche, Joerg Laufer, Fabian Klaus, Agathe Zürn, Ricco Lindner, Nathalie Strutz-Seebohm, Jeremy M. Tavaré, Christoph Boehmer, Monica almada, Undine E. Lang, Guiscard Seebohm, Florian Lang
Cell Physiol Biochem 2010;25:187-194 (DOI: 10.1159/000276569)

Abstract
PDF (889 KB)
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Diabetes Is Associated with Increased Rate of Cognitive Decline in Questionably Demented Elderly
Ramit Ravona-Springer, Xiaodong Luo, James Schmeidler, Michael Wysocki, Gerson Lesser, Michael Rapp, Karen Dahlman, Hillel Grossman, Vahram Haroutunian, Michal Schnaider Beeri
Dement Geriatr Cogn Disord 2010;29:68-74 (DOI: 10.1159/000265552)

Abstract
PDF (189 KB)
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Baseline Diabetic Status and Admission Blood Glucose Were Poor Prognostic Factors in the EPITHET Trial
D.A. De Silva, M. Ebinger, S. Christensen, M.W. Parsons, C. Levi, K. Butcher, P.A. Barber, C. Bladin, G.A. Donnan, S.M. Davis, Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) Investigators
Cerebrovasc Dis 2010;29:14-21 (DOI: 10.1159/000255969)

Abstract
PDF (217 KB)
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New-Onset Diabetes after Hemodialysis Initiation: Impact on Survival
Moro O. Salifu, Kevin C. Abbott, Serhat Aytug, Amir Hayat, Dhiren M. Haria, Syed Shah, Eli A. Friedman, Barbara G. Delano, Samy I. McFarlane, Frank P. Hurst, Peter L. Flom, Rahul M. Jindal
Am J Nephrol 2010;31:239-246 (DOI: 10.1159/000276542)

Abstract
PDF (170 KB)
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Genetic Susceptibility to Type 2 Diabetes Is Associated with Reduced Prostate Cancer Risk
Brandon L. Pierce, Habibul Ahsan
Hum Hered 2010;69:193-201 (DOI: 10.1159/000289594)

Abstract
PDF (201 KB)
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Is Cystatin C a Useful Marker in the Detection of Diabetic Kidney Disease?
Rodolfo L. Borges, Andréa H. Hirota, Beata M.R. Quinto, Arthur B. Ribeiro, Maria T. Zanella, Marcelo C. Batista
Nephron Clin Pract 2010;114:c127-c134 (DOI: 10.1159/000254385)

Abstract
PDF (194 KB)

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Original Paper Published in a Book
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Frontiers in Eating and Weight Regulation

Forum of Nutrition, Vol. 63
Editors: Langhans, W. (Schwerzenbach); Geary, N. (Schwerzenbach)
XII + 208 p., 28 fig., 1 in color, 4 tab., hard cover, 2010

Full Details

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Chapter of Interest:

Metabolic Imprinting in Obesity
Sullivan EL, Grove KL

Abstract
PDF (91 KB)

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Short Communication Published in a Journal
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Transient Hyperopia and Diabetes
Morteza Mehdizadeh, Mohammad H. Nowroozzadeh
Ophthalmologica 2010;224:63-63 (DOI: 10.1159/000235728)

Abstract
PDF (70 KB)

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2009 Publications

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Reviews Published in Journals
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MicroRNAs in Diabetes: Tiny Players in Big Disease
Amit K. Pandey, Priyanka Agarwal, Kirandeep Kaur, Malabika Datta
Cell Physiol Biochem 2009;23:221-232 (DOI: 10.1159/000218169)

Abstract
PDF (545 KB)
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Neuroprotection in Diabetic Encephalopathy
Seyyed Amirhossein Fazeli
Neurodegenerative Dis 2009;6:213-218 (DOI: 10.1159/000278694)

Abstract
PDF (157 KB)
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Interactions between the Endocrine and Exocrine Pancreas and Their Clinical Relevance
László Czakó, Péter Hegyi, Zoltán Rakonczay, Jr., Tibor Wittmann, Makoto Otsuki
Pancreatology 2009;9:351-359 (DOI: 10.1159/000181169)

Abstract
PDF (250 KB)

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Review Published in a Book
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European Nutrition and Health Report 2009

Forum of Nutrition, Vol. 62
Editor: Elmadfa, I. (Vienna)
XIV + 412 p., 87 fig., 162 tab., hard cover, 2009

Full Details

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Chapter of Interest:

Health and Lifestyle Indicators in the European Union

Abstract
PDF (2412 KB)

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Original Papers Published in Journals
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Evidence of Interaction between Type 2 Diabetes Susceptibility Genes and Dietary Fat Intake for Adiposity and Glucose Homeostasis-Related Phenotypes
Stephanie-May Ruchat, Cathy E. Elks, Ruth J.F. Loos, Marie-Claude Voh, S. John Weisnagel, Tuomo Rankinen, Claude Bouchard, Louis Pérusse
J Nutrigenet Nutrigenomics 2009;2:225-234 (DOI: 10.1159/000259341)

Abstract
PDF (220 KB)
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Waist-to-Height Ratio Is the Best Anthropometric Index in Association with Adverse Cardiorenal Outcomes in Type 2 Diabetes Mellitus Patients
O. Lamacchia, S. Pinnelli, D. Camarchio, S. Fariello, L. Gesualdo, G. Stallone, M. Cignarelli
Am J Nephrol 2009;29:615-619 (DOI: 10.1159/000194454)

Abstract
PDF (146 KB)
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Ghrelin and New Metabolic Frontiers
Aart Jan van der Lely
Horm Res 2009;71 (Suppl. 1):129-133 (DOI: 10.1159/000178055)

Abstract
PDF (132 KB)
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Microaneurysm Turnover Is a Biomarker for Diabetic Retinopathy Progression to Clinically Significant Macular Edema: Findings for Type 2 Diabetics with Nonproliferative Retinopathy
Sandrina Nunes, Isabel Pires, Andreia Rosa, Lilianne Duarte, Rui Bernardes, José Cunha-Vaz
Ophthalmologica 2009;223:292-297 (DOI: 10.1159/000213639)

Abstract
PDF (149 KB)
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Electron Impact Mass Spectroscopic Studies on Mouse Retinal Fatty Acids
Effect of Diabetes
K.R. Hegde, S.D. Varma
Ophthalmic Res 2009;42:9-14 (DOI: 10.1159/000219679)

Abstract
PDF (207 KB)
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Neutrophil Gelatinase-Associated Lipocalin as an Early Biomarker of Nephropathy in Diabetic Patients
Davide Bolignano, Antonio Lacquaniti, Giuseppe Coppolino, Valentina Donato, Maria Rosaria Fazio, Giacomo Nicocia, Michele Buemi
Kidney Blood Press Res 2009;32:91-98 (DOI: 10.1159/000209379)

Abstract
PDF (205 KB)
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Plasma Visfatin Concentrations in Subjects with Type 1 Diabetes Mellitus
F. Toruner, A.E. Altinova, N. Bukan, E. Arslan, E. Akbay, R. Ersoy, M. Arslan
Horm Res 2009;72:33-37 (DOI: 10.1159/000224338)

Abstract
PDF (127 KB)
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Urinary Fatty Acids and Liver-Type Fatty Acid Binding Protein in Diabetic Nephropathy
Hiroyo Sasaki, Atsuko Kamijo-Ikemori, Takeshi Sugaya, Kayoko Yamashita, Takeshi Yokoyama, Jyunki Koike, Takeo Sato, Takashi Yasuda, Kenjiro Kimura
Nephron Clin Pract 2009;112:c148-c156 (DOI: 10.1159/000214210)

Abstract
PDF (455 KB)
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Hypoglycemia Rates in the First Days of Life among Term Infants Born to Diabetic Mothers
Ayala Maayan-Metzger, Daniel Lubin, Jacob Kuint
Neonatology 2009;96:80-85 (DOI: 10.1159/000203337)

Abstract
PDF (154 KB)
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Prevalence and Risk Factors of Somatic and Autonomic Neuropathy in Prediabetic and Diabetic Patients
Wei-Chih Hsu, Amy Ming-Fang Yen, Horng-Huei Liou, Han-Cheng Wang, Tony Hsiu-Hsi Chen
Neuroepidemiology 2009;33:344-349 (DOI: 10.1159/000254571)

Abstract
PDF (156 KB)

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Original Papers Published in Books
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Early Life Origins of Human Health and Disease

Editors: Newnham, J.P. (Perth, W.A.); Ross, M.G. (Los Angeles, Calif.)
X + 224 p., 29 fig., 6 tab., hard cover, 2009

Full Details

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Chapters of Interest:

Fetal Programming of Type 2 Diabetes
Piekarz A, Ozanne SE

PDF (100 KB)
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Developmental Origins of Diabetes: Interventional Strategies
Simmons RA

PDF (159 KB)
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Pharmacology and Vitreoretinal Surgery

Developments in Ophthalmology, Vol. 44
Editor: Gandorfer, A. (Munich)
XII + 102 p., 30 fig., 13 in color, hard cover, 2009

Full Details

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Chapters of Interest:

Neuroprotection for Diabetic Retinopathy
Imai H, Singh RSJ, Fort PE, Gardner TW

Abstract
PDF (121 KB)
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VEGF Inhibitors and Vitrectomy for Diabetic Vitreoretinopathy
Cury, Jr CE, Rodrigues EB, Meyer CH, Farah ME

Abstract
PDF (276 KB)

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Short Communications Published in Journals
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Pancreatology and the Web: Diabetes
Gwen Lomberk
Pancreatology 2009;9:200-202 (DOI: 10.1159/000187722)

Abstract
PDF (57 KB)
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Case Report: Transient Hyperopia after Intensive Treatment of Hyperglycemia in Newly Diagnosed Diabetes
Shu-Fang Lin, Po-Kang Lin, Fang-Ling Chang, Rong-Kung Tsai
Ophthalmologica 2009;223:68-71 (DOI: 10.1159/000173714)

Abstract
PDF (70 KB)
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Evaluation of Modified Portable Digital Camera for Screening of Diabetic Retinopathy
Kakarla V. Chalam, Vikram S. Brar, Ravi Keshavamurthy
Ophthalmic Res 2009;42:60-62 (DOI: 10.1159/000219687)

Abstract
PDF (167 KB)
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Primers on Molecular Pathways The Insulin Pathway
Gwen Lomberk, Raul Urrutia
Pancreatology 2009;9:203-205 (DOI: 10.1159/000200021)

Abstract
PDF (138 KB)

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Further Reading

(Not included in the free-access in focus collection)

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Yearbook of Pediatric Endocrinology 2009

Endorsed by the European Society for Paediatric Endocrinology (ESPE)
Yearbook of Pediatric Endocrinology
Editors: Carel, J.-C. (Paris); Hochberg, Z. (Haifa)
X + 250 p., 1 fig., 1 tab., hard cover, 2009

Full Details

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Cardiovascular Diabetology: Clinical, Metabolic and Inflammatory Facets

Advances In Cardiology, Vol. 45
Editors: Fisman, E.Z. (Holon); Tenenbaum, A. (Tel-Hashomer)
XIV + 174 p., 23 fig., 5 tab., hard cover, 2008

Full Details

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Development of the Pancreas and Neonatal Diabetes

1st ESPE Advanced Seminar in Developmental Endocrinology, Paris 2007
Endocrine Development, Vol. 12
Editors: Scharfmann, R. (Paris); Shield, J.P.H. (Bristol)
VIII + 142 p., 21 fig., 11 in color, 9 tab., hard cover, 2007

Full Details

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Nutritional Management of Diabetes Mellitus and Dysmetabolic Syndrome

Nestlé Nutrition Institute Workshop Series: Clinical & Performance Program, Vol. 11
Editors: Bantle, J.P. (Minneapolis, Minn.); Slama, G. (Paris)
XIV + 224 p., 19 fig., 25 tab., hard cover, 2006

Full Details

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Teuscher, A. (Bern)
Insulin A Voice for Choice

XIV + 82 p., 9 fig., 8 tab., soft cover, 2007

Full Details

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