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Vascular Calcification and Osteoprotegrin in Chronic Kidney Disease

Lenhard M.J.a, c · Maser R.E.a, b

Author affiliations

aDiabetes and Metabolic Research Center, Christiana Care Health System, and bDepartment of Medical Laboratory Sciences, University of Delaware, Newark, and cDiabetes and Metabolic Diseases Center, Christiana Care Health System, Wilmington, DE, USA

Corresponding Author

M. James Lenhard, MD

Diabetes and Metabolic Diseases Center

Christiana Care Health System

Wilmington, DE 19801 (USA)

E-Mail jlenhard@christianacare.org

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Am J Nephrol 2017;46:37-38

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Abstract of Editorial


  1. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY: Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004;351:1296-1305.
  2. Budoff MJ, Young R, Lopez VA, et al: Progression of coronary calcium and incident coronary heart disease events: MESA (Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol 2013;61:1231-1239.
  3. Goodman WG, Goldin J, Kuizon BD, et al: Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis. N Engl J Med 2000;342:1478-1483.
  4. Vattikuti R, Towler DA: Osteogenic regulation of vascular calcification: an early perspective. Am J Physiol Endocrinol Metab 2004;286:E686-E696.
  5. Chen JC, Budoff MJ, Reilly MP, et al: Coronary artery calcification and risk of cardiovascular disease and death among patients with chronic kidney disease. JAMA Cardiol 2017, Epub ahead of print.
  6. Avila M, Mora C, Prado MC, Zavala M, Paniagua R; Mexican Collaborative Group: Osteoprotegerin is the strongest predictor for progression of arterial calcification in peritoneal dialysis patients. Am J Nephrol 2017;46:39-46.
  7. Wu M, Rementer C, Giachelli CM: Vascular calcification: an update on mechanisms and challenges in treatment. Calcif Tissue Int 2013;93:365-373.
  8. Dhore CR, Cleutjens JP, Lutgens E, et al: Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques. Arterioscler Thromb Vasc Biol 2001;21:1998-2003.

Article / Publication Details

Published online: June 15, 2017
Issue release date: July 2017

Number of Print Pages: 2
Number of Figures: 0
Number of Tables: 0

ISSN: 0250-8095 (Print)
eISSN: 1421-9670 (Online)

For additional information: https://www.karger.com/AJN

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