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Clinical and Laboratory Investigations

Relevance of Thyroiditis and of Other Autoimmune Diseases in Children with Vitiligo

Iacovelli P. · Sinagra J.L.M. · Vidolin A.P. · Marenda S. · Capitanio B. · Leone G. · Picardo M.

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San Gallicano Institute, IRCCS, Roma, Italy

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Dermatology 2005;210:26–30

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Article / Publication Details

First-Page Preview
Abstract of Clinical and Laboratory Investigations

Received: June 13, 2004
Accepted: August 30, 2004
Published online: January 28, 2005
Issue release date: December 2004

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 3

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: https://www.karger.com/DRM

Abstract

Background: Studies that clearly define the possible association of childhood vitiligo with autoimmune and/or endocrine diseases are lacking. Objective: To examine the presence of autoimmune disorders, in particular of thyroid disease, in paediatric patients with vitiligo and investigate the utility of such screening in these patients. Methods: One hundred and twenty-one paediatric patients (40 males, 81 females) with vitiligo were grouped in segmental and non-segmental vitiligo. All patients were screened for thyroid disease. Results: 13 out of 121 patients had different degrees of thyroid parameter alterations. These patients were all affected by the non-segmental type while none of those with the segmental form presented thyroid alterations. Conclusion: In paediatric patients with non-segmental vitiligo, a significant incidence of thyroid dysfunction was found. Since vitiligo usually appears before the development of the thyroid disease, it may be useful to screen thyroid autoantibodies in all paediatric patients with non-segmental vitiligo who present symptoms related to thyroid disease.

© 2005 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Clinical and Laboratory Investigations

Received: June 13, 2004
Accepted: August 30, 2004
Published online: January 28, 2005
Issue release date: December 2004

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 3

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: https://www.karger.com/DRM


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