Animal Models of Cancer Predisposition Syndromes
Editor(s): Hino O. (Tokyo)
Hiai H. (Kyoto)
Publication year: 1999
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Progress in Tumor Research , Vol. 35
Editor(s): Stahel R.A. (Zurich)
Peters S. (Lausanne)
VIII + 176 p., 29 fig., 3 in color, 21 tab., hard cover, 1999
This book brings together some of the most recent advances made in the genetic analysis of cancer susceptibility using animal models. Leading investigators in the field present model systems for studying cancers including liver and stomach cancer, breast cancer, myeloid leukemia, retrovirus-induced lymphoma, pulmonary adenoma and familial adenomatous polyposis. An overview of transgenic and gene knockout mice is given, and in several chapters the implications of these findings for human cancers are discussed. Providing an excellent survey of the field, the book is recommended reading for all scientists and graduate students in experimental cancer research and cancer genomics.