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Alternatives to Animals in the Development and Control of Biological Products for Human and Veterinary Use

Congress, London, September 1998

Editor(s): Sesardic D. (Potters Bar) 
Brown F. (Greenport, N.Y.) 
Hendriksen C.F.M. (Bilthoven) 
Society/Societies: International Association of Biological Standardization 

Status: available   
Publication year: 1999
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This book belongs to
Developments in Biologicals , Vol. 101
XII + 340 p., 48 fig., 41 tab., soft cover, 1999
Status: available   
ISSN: 1424-6074
e-ISSN: 1662-2960

Interest in the use of alternative in vitro reduction and refinement methods in the development and control of biological products has increased considerably in the last few years. The issues raised are of concern to the scientific community as well as to manufacturers, regulatory authorities and those involved in animal ethics and welfare. A large number of physicochemical, immunochemical, biochemical and cell biological methods have been proposed for the replacement, reduction and refining of animal tests in the development and control of human and veterinary vaccines and other biological products. However, the implementation, validation and ultimate regulatory acceptance of these procedures are still at a very early stage. This volume contains the proceedings of a meeting, which brought together research scientists, manufacturers and regulators with the aim of promoting an exchange of scientific knowledge and increasing awareness of the importance of validation studies.