Login to MyKarger

New to MyKarger? Click here to sign up.

Login with Facebook

Forgot your password?

Authors, Editors, Reviewers

For Manuscript Submission, Check or Review Login please go to Submission Websites List.

Submission Websites List

Institutional Login
(Shibboleth or Open Athens)

For the academic login, please select your country in the dropdown list. You will be redirected to verify your credentials.


Angiogenesis in Hematology

Editor(s): Giustolisi R. (Catania) 
Di Raimondo F. (Catania) 

Status: available   
Publication year: 2001
Buy this book
Digital Version: CHF 39.00, EUR 36.00, USD 46.00
Print Version: CHF 39.00, EUR 36.00, USD 46.00
The final prices may differ from the prices shown due to specifics of VAT rules, postage and handling.
Order this title

You already have online access to this title. If you would like to buy a personal digital or print copy, please click here.

This special issue reviews various aspects of angiogenesis in hematological diseases and considers perspectives of new therapeutic approaches. The initial chapters focus on the role of mediators of angiogenesis, the effect of hematopoietic growth factors on endothelial cell functions and on the relationship between angiogenesis and hematopoiesis. Subsequently, the importance of angiogenesis in the pathophysiology of several hematological diseases is discussed. Besides multiple myeloma - the first disease in which the role of angiogenesis has been ascertained - evidence is provided on the relevance of dysregulated angiogenesis in acute leukemias, myelodysplastic syndromes, myeloproliferative disorders and non-Hodgkin’s lymphoma. In all these diseases, neo-angiogenesis is indicated by the increased vascularity in bone marrow and high levels of several angiogenic factors. The value of these factors in the clinical outcome of hematological diseases and the rationale for the use of anti-angiogenic treatments as a new therapeutical approach are addressed. Finally, a model of aberrant angiogenesis as the cause of an hereditary hemorrhagic disorder is described.
A valuable resource for any hematologist, this publication will also be of interest to researchers and clinicians in oncology and internal medicine.