Adipose Tissue Development
From Animal Models to Clinical Conditions
3rd ESPE Advanced Seminar in Developmental Endocrinology, Paris, March 2009
Editor(s): Levy-Marchal C. (Paris)
Pénicaud L. (Dijon)
Publication year: 2010
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Endocrine Development , Vol. 19
Editor(s): Mullis P.-E. (Bern)
X + 96 p., 11 fig., 3 tab., hard cover, 2010
These proceedings cover the nervous regulation of both white and brown adipose tissue mass. Different physiological parameters such as metabolism (lipolysis and thermogenesis) and secretory activity (leptin and other adipokines) are reviewed. The plasticity of adipose tissue (proliferation, differentiation and apoptosis) showing the presence of a neural feedback loop between adipose tissue and the brain, which plays a major role in the regulation of energy homeostasis, is discussed.
Merging basic knowledge and various clinical conditions, this thorough review is of great interest to both scientists and physicians, in particular pediatricians, interested in obesity, endocrinology and nutrition.