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Antituberculosis Chemotherapy

Editor(s): Donald P.R. (Tygerberg) 
van Helden P.D. (Tygerberg) 

Status: available   
Publication year: 2011
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This book belongs to
Progress in Respiratory Research , Vol. 40
Editor(s): Herth F.J.F. (Heidelberg) 
X + 252 p., 53 fig., 2 in color, 50 tab., hard cover, 2011
Status: available   
ISSN: 1422-2140
e-ISSN: 1662-3932

Read the reviews

‘The content of the book is organized uniquely in a review article format. The book is replete with comprehensive, well-referenced tables, and there are plenty of reference citations. Each chapter provides an extensive review and fully referenced discussion of important areas in TB management. The style is easy to read and the content logically sequenced. This book is an ideal source of reference for TB researchers, physicians, chest specialists, specialist in infectious diseases, and other clinicians who manage patients with TB and require a knowledge of the current treatment options, as well as evidence supporting future treatment options.’

Alladi Mohan (The National Medical Journal of India, Vol. 25, No. 3, May/June 2012)

«Zusammenfassend stellt dieser Band zur antituberkulotischen Chemotherapie eine exzellente Übersicht zur Historie, zum gegenwärtigen Stand und zu den zukünftigen Entwicklungen auf diesem Gebiet dar. Ausgewiesene internationale Experten haben alle wesentlichen Aspekte der Tbc-Behandlung in gut lesbarer Form mit überzeugenden Abbildungen und Tabellen dargestellt. Dieses Buch kann jedem mit der Behandlung der Tuberkulose befassten Arzt uneingeschränkt und nachdrücklich als aktuelles Standardwerk zu diesem Thema empfohlen werden.»

Prof. Dr. Hartmut Lode, Berlin (Arzneimitteltherapie Bd. 30, Nr. 6, Juni 2012)

‘The book is well organized, dividing the contents into the past, present and future of tuberculosis treatment, providing the reader with a historical perspective of the advances on the field of antituberculosis chemotherapy in the last 70 years, and how and why the current issues have emerged. The balance of the subject matter is appropriate, addressing the key topics in depth. Noteworthy are the chapters that specifically focus on aspects of paediatric tuberculosis chemotherapy and clinical trials. It is timely to devote a chapter to paediatric tuberculosis as there is still debate on the best way to evaluate new anti-TB drugs and regimens.’

Timothy McHugh, University College London (Microbiology Today, May 2012)

‘This book is a comprehensive collection of well written reviews on the treatment of TB. …the editors are to be congratulated on producing a thoroughly useful reference book which is relevant and readable for both pharmacologists and clinicians treating patients with TB.’

Dr. Heather Milburn, Guy's and St. Thomas' NHS Foundation Trust, London, UK
(British Journal of Clinical Pharmacology, Vol. 74, No. 3, 2012)
With contributions by some of the most well-known specialists in tuberculosis research
Tuberculosis (TB) remains one of the major infectious diseases of mankind although drugs for its treatment have been available for nearly 60 years. The standard short-course 6-month regimen used since about 1980 has helped to save millions of lives, but co-infection with HIV has had a devastating effect on the epidemic, and multidrug-resistant TB is a growing problem, particularly in communities with a high incidence of HIV. Following the declaration by the WHO in the early 1990s that TB was a ‘global health emergency’, interest in TB research and the development of new drugs has increased significantly.
This volume reviews anti-TB chemotherapy with the emphasis on the actions and pharmacology of existing drugs and the development and evaluation of new agents. A close look is taken at new research regarding our existing drugs by some of the best-known specialists in the field, and historical aspects of these agents are reviewed from a modern perspective. The prospects for the introduction of new drugs and different approaches of how to assess them in adults and in children are discussed in detail. Several papers address the problems associated with drug resistance, its spread and diagnosis.
Compiled by two editors from Cape Town, which has a particularly high incidence of TB and is a centre of tuberculosis research, this publication is an indispensable reference for anyone involved in the management of TB either as a researcher, clinician or administrator, and those working in drug development.